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©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Apr 16, 2019; 11(4): 271-280
Published online Apr 16, 2019. doi: 10.4253/wjge.v11.i4.271
Published online Apr 16, 2019. doi: 10.4253/wjge.v11.i4.271
Efficacy and safety of standard and anti-reflux self-expanding metal stent: A systematic review and meta-analysis of randomized controlled trials
Sudha Pandit, Hrishikesh Samant, James Morris, Department of Gastroenterology and Hepatology, Louisiana State University Health Science Center, Shreveport, LA 71103, United States
Steven J Alexander, Department of Cell Biology and Physiology, Louisiana State University, School of Medicine, Shreveport, LA 71103, United States
Author contributions: Pandit S and Samant H contributed equally to prepare this manuscript. Pandit S and Samant H designed study, performed data acquisition, analyzed data, drafted manuscript, final approval; Morris J analyzed data, edited manuscript; Alexander S edited manuscript, final approval.
Conflict-of-interest statement: The authors have no conflicting financial interests to disclose.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Sudha Pandit, MD, Academic Fellow, Department of Gastroenterology and Hepatology, Louisiana State University, Health Science Center, 1501 Kings HWY, Shreveport, LA 71103, United States. spandi@lsuhsc.edu
Telephone: +1-318-675-5982 Fax: +1-318-675-5957
Received: February 18, 2019
Peer-review started: February 18, 2019
First decision: February 26, 2019
Revised: March 11, 2019
Accepted: April 8, 2019
Article in press: April 9, 2019
Published online: April 16, 2019
Peer-review started: February 18, 2019
First decision: February 26, 2019
Revised: March 11, 2019
Accepted: April 8, 2019
Article in press: April 9, 2019
Published online: April 16, 2019
Core Tip
Core tip: In this meta-analysis, we studied and compared the traditional standard self-expanding metal stent and anti-reflux stent in terms of their efficacy and safety. We included 8 randomized controlled trials in our meta-analysis from 3 different databases. We expected anti-reflux stent with valves, as its name suggests, to show improvement in reflux symptom score, however, this was not observed in our study. This review study shows that there is no difference between standard stent and anti-reflux stent in terms of improving reflux symptom and dysphagia score. This study also confirms that there is no difference in terms of complications including stent migration, bleeding, and obstruction between standard stent and anti-reflux stent.