Systematic Review
Copyright ©The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Oct 16, 2018; 10(10): 308-321
Published online Oct 16, 2018. doi: 10.4253/wjge.v10.i10.308
Systematic review of safety and efficacy of therapeutic endoscopic-retrograde-cholangiopancreatography during pregnancy including studies of radiation-free therapeutic endoscopic-retrograde-cholangiopancreatography
Mitchell S Cappell, Stavros Nicholas Stavropoulos, David Friedel
Mitchell S Cappell, Division of Gastroenterology and Hepatology, William Beaumont Hospital, Royal Oak, MI 48073, United States
Mitchell S Cappell, Oakland University William Beaumont School of Medicine, Royal Oak, MI 48073, United States
Stavros Nicholas Stavropoulos, David Friedel, Division of Gastroenterology, New York University Winthrop Medical Center, Mineola, NY 11501, United States
Author contributions: Cappell MS had the most important contributions to the organization, writing, and editing of the manuscript; Stavropoulos SN and Friedel D contributed very significantly to all aspects of the paper, including the organization, writing, and editing of the manuscript; the final manuscript was reviewed, corrected, and approved by all three authors.
Conflict-of-interest statement: All authors have no conflicts of interest to report.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Mitchell S Cappell, FACG, MD, PhD, Chief Doctor, Professor, Division of Gastroenterology and Hepatology, William Beaumont Hospital, 3535 W. Thirteen Mile Road, Royal Oak, MI 48073, United States. mitchell.cappell@beaumont.edu
Telephone: +11-1248-5511227 Fax: +11-1248-5517581
Received: April 28, 2018
Peer-review started: April 28, 2018
First decision: May 18, 2018
Revised: July 13, 2018
Accepted: August 26, 2018
Article in press: August 27, 2018
Published online: October 16, 2018
Core Tip

Core tip: This work systematically reviews safety/efficacy of therapeutic endoscopic-retrograde-cholangiopancreatography (ERCP) performed during pregnancy, considering fetal viability, fetal teratogenicity, premature delivery, and future development of the infant after parturition. Systematic computerized literature search was performed using PubMed with key words “ERCP” and “pregnancy”. Two clinicians independently reviewed the literature, and decided on which articles to incorporate in this review based on pre-arranged prioritization and consensus. Clinical experience with performing ERCP during pregnancy is burgeoning, with > 500 cases of therapeutic ERCP reported in the literature, plus a national registry study of 58 patients.