Minireviews
Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Sep 25, 2015; 7(13): 1088-1095
Published online Sep 25, 2015. doi: 10.4253/wjge.v7.i13.1088
Upper non-variceal gastrointestinal bleeding - review the effectiveness of endoscopic hemostasis methods
Mirosław Szura, Artur Pasternak
Mirosław Szura, Artur Pasternak, First Department, General, Oncological and Gastrointestinal Surgery, Jagiellonian University Medical College, 31-501 Krakow, Poland
Artur Pasternak, Poland and Department of Anatomy, Jagiellonian University Medical College, 31-034 Krakow, Poland
Author contributions: Szura M and Pasternak A contributed equally to this work; Szura M and Pasternak A were responsible for the literature review; Pasternak A wrote the initial draft; and Szura M prepared the final version of the paper.
Conflict-of-interest statement: The authors have no conflict of interest related to the manuscript.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Mirosław Szura, MD, PhD, First Department, General, Oncological and Gastrointestinal Surgery, Jagiellonian University Medical College, 40 Kopernika St., 31-501 Krakow, Poland. msszura@gmail.com
Telephone: +48-12-4248007 Fax: +48-12-4248007
Received: April 24, 2015
Peer-review started: April 24, 2015
First decision: June 2, 2015
Revised: June 17, 2015
Accepted: August 30, 2015
Article in press: September 7, 2015
Published online: September 25, 2015
Processing time: 153 Days and 17.7 Hours
Abstract

Upper non-variceal gastrointestinal bleeding is a condition that requires immediate medical intervention and has a high associated mortality rate (exceeding 10%). The vast majority of upper gastrointestinal bleeding cases are due to peptic ulcers. Helicobacter pylori infection, non-steroidal anti-inflammatory drugs and aspirin are the main risk factors for peptic ulcer disease. Endoscopic therapy has generally been recommended as the first-line treatment for upper gastrointestinal bleeding as it has been shown to reduce recurrent bleeding, the need for surgery and mortality. Early endoscopy (within 24 h of hospital admission) has a greater impact than delayed endoscopy on the length of hospital stay and requirement for blood transfusion. This paper aims to review and compare the efficacy of the types of endoscopic hemostasis most commonly used to control non-variceal gastrointestinal bleeding by pooling data from the literature.

Keywords: Upper gastrointestinal bleeding; Non-variceal bleeding; Endoscopic hemostasis; Endoscopic therapy

Core tip: Review and comparison the efficacy of the most commonly used types of endoscopic hemostasis for the control of non-variceal gastrointestinal bleeding in clinical practice by pooling data from the literature.