Nonaka K, Namoto M, Kitada H, Shimizu M, Ochiai Y, Togawa O, Nakao M, Nishimura M, Ishikawa K, Arai S, Kita H. Usefulness of the DL in ME with NBI for determining the expanded area of early-stage differentiated gastric carcinoma. World J Gastrointest Endosc 2012; 4(8): 362-367 [PMID: 22912910 DOI: 10.4253/wjge.v4.i8.362]
Corresponding Author of This Article
Hiroto Kita, MD, PhD, Department of Gastroenterology, Saitama Medical University International Medical Center, Saitama 350-1298, Japan. hkita@saitama-med.ac.jp
Article-Type of This Article
Brief Article
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Kouichi Nonaka, Yasutoshi Ochiai, Osamu Togawa, Masamitsu Nakao, Makoto Nishimura, Keiko Ishikawa, Shin Arai, Hiroto Kita, Department of Gastroenterology, Saitama Medical University International Medical Center, Saitama 350-1298, Japan
Masaaki Namoto, Department of Gastroenterology, Kitakyushu Municipal Medical Center, Fukuoka 802-0077, Japan
Hideki Kitada, Department of Gastroenterology, Japanese Red Cross Kumamoto Hospital, Kumamoto 861-8520, Japan
Michio Shimizu, Department of Pathology, Saitama Medical University International Medical Center, Saitama 350-1298, Japan
Author contributions: Nonaka K made substantial contributions to conception and design of the study, analysis and interpretation of date, drafting and revision of the manuscript, perform the majority of experiments; Namoto M and Kitada H performed the experiments; Shimizu M made contributions to pathological analysis and interpretation of data; Ochiai Y, Togawa O, Nakao M, Nishimura M, Ishikawa K and Arai S provided the support for this work; Kita H approved of the final version of the manuscript.
Correspondence to: Hiroto Kita, MD, PhD, Department of Gastroenterology, Saitama Medical University International Medical Center, Saitama 350-1298, Japan. hkita@saitama-med.ac.jp
Telephone: +81-4-29844111 Fax: +81-4-29844741
Received: September 7, 2011 Revised: July 10, 2012 Accepted: August 8, 2012 Published online: August 16, 2012
Abstract
AIM: To investigate whether magnifying endoscopy with narrow band imaging (ME-NBI) is useful for evaluating the area of superficial, depressed- or flat-type differentiated adenocarcinoma of the stomach.
METHODS: This procedure was performed in Saitama Medical University International Medical Center, Japanese Red Cross Kumamoto Hospital and Kitakyushu Municipal Medical Center. The subjects were 31 patients in whom biopsy findings, from superficial, depressed- or flat-type gastric lesion, suggested differentiated adenocarcinoma in the above 3 hospitals between January and December 2009. Biopsy was performed on the lesion and non-lesion sides of a boundary (imaginary boundary) visualized on ME-NBI. The results were pathologically investigated. We evaluated the accuracy of estimating a demarcation line (DL) on ME-NBI in comparison with biopsy findings as a gold standard.
RESULTS: The DL that could be recognized at 2 points on the orifice and anal sides of each lesion during ME-NBI was consistent with the pathological findings in 22 patients with 0-IIc lesions, 7 with 0-IIb lesions, and 2 with 0-IIb + IIc lesions, showing an accuracy of 100%.
CONCLUSION: The results suggest the usefulness of ME-NBI for evaluating the area of superficial, depressed- and flat-type differentiated adenocarcinoma of the stomach.
