Hoffman A, Rahman F, Prengel S, Schuchmann M, Gotz M, Moehler M, Galle PR, Li Z, Kalloo AN, Kiesslich R. Mini-laparoscopy in the endoscopy unit: Safety and outcomes in over one thousand patients. World J Gastrointest Endosc 2011; 3(1): 6-10 [PMID: 21258600 DOI: 10.4253/wjge.v3.i1.6]
Corresponding Author of This Article
Arthur Hoffman, MD, First Department of Internal Medicine, Johannes Gutenberg University of Mainz, Langenbeckstr. 1, Mainz 55101, Germany. ahoff66286@aol.com
Article-Type of This Article
Brief Articles
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World J Gastrointest Endosc. Jan 16, 2011; 3(1): 6-10 Published online Jan 16, 2011. doi: 10.4253/wjge.v3.i1.6
Mini-laparoscopy in the endoscopy unit: Safety and outcomes in over one thousand patients
Arthur Hoffman, Fareed Rahman, Sarah Prengel, Marcus Schuchmann, Martin Gotz, Markus Moehler, Peter Robert Galle, Ziping Li, Anthony Nicholas Kalloo, Ralf Kiesslich
Arthur Hoffman, Fareed Rahman, Sarah Prengel, Marcus Schuchmann, Martin Gotz, Markus Moehler, Peter Robert Galle, Ralf Kiesslich, First Department of Internal Medicine, Johannes Gutenberg University Mainz, Mainz 55101, Germany
Ziping Li, Anthony Nicolas Kalloo, Department of Gastroenterology and Hepatology, Johns Hopkins University, Baltimore, MD 21287, Unites States
Author contributions: Hoffmann A and Rahman F contributed equally to this article; Hoffman A was responsible for study design, performance of mini-laparoscopy and data analysis; Rahman F was responsible for data analysis, preparation of the manuscript and performance of mini-laparoscopy; Prengel S collected and analyzed data; Schuchmann M, Gotz M and Moehler M participated in performance of mini-laparoscopy; Galle PR was the chief of department and was involved with data discussion; Kiesslich R was the chief of the endoscopy branch and was involved with data discussion; and Li Z and Kalloo AN also participated in the study design and discussion.
Correspondence to: Arthur Hoffman, MD, First Department of Internal Medicine, Johannes Gutenberg University of Mainz, Langenbeckstr. 1, Mainz 55101, Germany. ahoff66286@aol.com
Telephone: +49-6131-177299 Fax: +49-6131-175552
Received: September 19, 2010 Revised: December 6, 2010 Accepted: December 13, 2010 Published online: January 16, 2011
Abstract
AIM: To investigate the safety of consecutive mini-laparoscopy guided liver biopsies for the diagnosis and staging of liver diseases.
METHODS: In this study we retrospectively analyzed the safety of mini-laparoscopic liver biopsy performed in an endoscopy unit in 1071 patients. We measured the incidence of bleeding and evaluated the management and outcome of bleeding interventions.
RESULTS: The most common etiologies of liver injury were viral hepatitis and autoimmune liver disease. 250 patients had macroscopically and histologically proven cirrhosis. 13 patients had no pathological findings. 33% of all patients had bleeding that required argon plasma coagulation of the puncture site during laparoscopy. Significant bleeding occurred more often in patients with liver cirrhosis compared to non-cirrhotic liver diseases but was effectively treated with laparoscopic coagulation.
CONCLUSION: In conclusion, mini-laparoscopy liver biopsy can be performed safely and effectively in high risk patients with advanced liver disease; mini-laparoscopy with liver biopsy can be done safely in an endoscopy unit.
