Editorial
Copyright ©2010 Baishideng. All rights reserved.
World J Gastrointest Endosc. Jul 16, 2010; 2(7): 237-243
Published online Jul 16, 2010. doi: 10.4253/wjge.v2.i7.237
Contrast enhanced endoscopic ultrasound: More than just a fancy Doppler
Rachid M Mohamed, Brian M Yan
Rachid M Mohamed, Brian M Yan, Division of Gastroenterology, Department of Medicine, University of Calgary, Calgary, Alberta T2N-4N1, Canada
Author contributions: Both authors contributed equally and significantly to the conceptual framework and drafting of this manuscript; Mohamed RM completed the literature review, wrote the manuscript, and approved the final version for publication; and Yan BM originated the concept of the manuscript, provided critical review and revisions, and approved the final version for publication.
Correspondence to: Brian M Yan, MD, FRCPC, Clinical Assistant Professor of Medicine, Division of Gastroenterology, Department of Medicine, University of Calgary, Rm 6D16 Teaching Wellness and Research Building, 3280 Hospital Drive NW, Calgary, Alberta T2N-4N1, Canada. bmyan@ucalgary.ca
Telephone: +1-403-5925033 Fax: +1-403-5925090
Received: January 21, 2010
Revised: May 28, 2010
Accepted: June 4, 2010
Published online: July 16, 2010
Abstract

Contrast enhanced endoscopic ultrasound (CEUS) is a new modality that takes advantage of vascular structure and blood flow to distinguish different clinical entities. Contrast agents are microbubbles that oscillate when exposed to ultrasonographic waves resulting in characteristic acoustic signals that are then converted to colour images. This permits exquisite imaging of macro- and microvasculature, providing information to help delineate malignant from non-malignant processes. The use of CEUS may significantly increase the sensitivity and specificity over conventional endoscopic ultrasound. Currently available contrast agents are safe, with infrequent adverse effects. This review summarizes the theory and technique behind CEUS and the current and future clinical applications.

Keywords: Endoscopic ultrasound, Contrast enhancement, Microbubble