Zheng L, Shi YQ, Xue T, Duan SL. Evaluating the detection rate and pathological features of polyps in patients with upper gastrointestinal endoscopy. World J Gastrointest Endosc 2025; 17(5): 105471 [DOI: 10.4253/wjge.v17.i5.105471]
Corresponding Author of This Article
Sheng-Lei Duan, Department of Gastroenterology, Shaanxi Hospital of Traditional Chinese Medicine, No. 4 Xihuamen Street, Lianhu District, Xi’an 730000, Shaanxi Province, China. 281930369@qq.com
Research Domain of This Article
Oncology
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Endosc. May 16, 2025; 17(5): 105471 Published online May 16, 2025. doi: 10.4253/wjge.v17.i5.105471
Evaluating the detection rate and pathological features of polyps in patients with upper gastrointestinal endoscopy
Lie Zheng, Yong-Quan Shi, Tao Xue, Sheng-Lei Duan
Lie Zheng, Sheng-Lei Duan, Department of Gastroenterology, Shaanxi Hospital of Traditional Chinese Medicine, Xi’an 730000, Shaanxi Province, China
Yong-Quan Shi, Department of Gastroenterology, Xijing Hospital Affiliated to Air Force Medical University, Xi’an 710032, Shaanxi Province, China
Tao Xue, Department of Gastroenterology, People’s Hospital of Jishan County, Yuncheng 043200, Shanxi Province, China
Author contributions: Zheng L and Xue T contributed to the conception and design of the study, wrote the manuscript, designed the clinical trials, and analyzed the data; Shi YQ, Xue T, and Duan SL contributed to the literature search; All authors reviewed and endorsed the final manuscript.
Supported by the Shaanxi Province Traditional Chinese Medicine Research and Innovation Talent Plan Project, No. TZKN-CXRC-16; Project of Shaanxi Administration of Traditional Chinese Medicine, No. SZYKJCYC-2025-JC-010; Shaanxi Province Outstanding TCM Talents Training Project Training Object in 2025; Xi’an Science and Technology Plan Project, No. 23YXYJ0162; and Shaanxi Province Key Research and Development Plan Project-Social Development Field, No. S2025-YF-YBSF-0391.
Institutional review board statement: This study was approved by the Medical Ethics Committee of Shaanxi Hospital of Traditional Chinese Medicine and People’s Hospital of Jishan County (Approval No. AF/SC-03/01.2).
Informed consent statement: Written informed consent was obtained from the patients and any accompanying images. Patients gave consent for their personal or clinical details along with any identifying images to be published in this study. all authors have read and approved the manuscript.
Conflict-of-interest statement: The authors have no conflicts of interest to declare.
Data sharing statement: No additional data are available.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Sheng-Lei Duan, Department of Gastroenterology, Shaanxi Hospital of Traditional Chinese Medicine, No. 4 Xihuamen Street, Lianhu District, Xi’an 730000, Shaanxi Province, China. 281930369@qq.com
Received: January 24, 2025 Revised: February 19, 2025 Accepted: April 2, 2025 Published online: May 16, 2025 Processing time: 108 Days and 23.4 Hours
Abstract
BACKGROUND
The incidence of gastric polyps (GPs) has ranged from 0.30% to 6.8% in various studies. Most GPs include hyperplastic polyps (HPs), fundic gland polyps (FGPs), and adenomatous polyps (APs). Although APs have a high malignant potential, HPs have a low risk of potential harm, whereas sporadic FGPs have no malignant potential. It is not enough to determine the type and displacement of a polyp by biopsy alone; therefore, some polyps may require an extensive biopsy or complete resection.
AIM
To evaluate the detection rate and pathological features of polyps in patients undergoing upper gastrointestinal endoscopy.
METHODS
This retrospective study included patients with GPs or polyphenic lesions with polyps or malignant histology found in polyps or by gastroscopy at the Department of Gastroenterology at the Shaanxi Provincial Hospital of Traditional Chinese Medicine from 2019 to 2023.
RESULTS
In a series of 10000 patients who underwent upper gastrointestinal endoscopy, 384 (3.84%) had GPs. There were 98 males (25.5%) and 286 females (74.5%). The mean age of patients was 62.8 ± 10.4 (36-75) years. The frequencies of HPs, APs, and FGPs were 88.5%, 5.2%, and 2.1%, respectively. The polyp size of 274 patients (71.3%) was ≤ 1 cm. Polyps were found in 262 cases (68.2%). The most common sites for polyps were the lumen and body of the intestine. Endoscopic polypectomy was performed in 128 patients. Bleeding events were observed and endoscopic treatment was required after endoscopic polypectomy.
CONCLUSION
The incidence of GPs was low. HPs were the most common types of GPs. Of note, as GPs have the potential to develop into adenocarcinoma or precancerous lesions, we suggest that appropriate GP resection technology (e.g., biopsy forceps or mesenchymal resection) be applied.
Core Tip: Gastric polyps (GPs) are a common clinical disease. In recent years, with the change in dietary habits, the incidence of GPs is increasing in China. GPs are usually found by gastroscopy. Some GPs may have malignant potential and are associated with hereditary diseases. Therefore, early detection and biopsy examination are important in clinical practice to better reduce the rate of cancer.
