Retrospective Study
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Feb 16, 2021; 13(2): 45-55
Published online Feb 16, 2021. doi: 10.4253/wjge.v13.i2.45
Complication rates in emergent endoscopy for foreign bodies under different sedation modalities: A large single-center retrospective review
Ming-Han Cha, Rashi Sandooja, Saher Khalid, Nicole Lao, Joseph Lim, Roshan Razik
Ming-Han Cha, Rashi Sandooja, Saher Khalid, Nicole Lao, Joseph Lim, Department of Internal Medicine, Cleveland Clinic Akron General, Akron, OH 44307, United States
Roshan Razik, Department of Gastroenterology, Cleveland Clinic Akron General, Akron, OH 44307, United States
Author contributions: Razik R and Cha MH conceived and planned the retrospective chart review; Cha MH, Sandooja R, Khalid S, Lim J and Lao N carried out the chart review process; Cha MH and Razik R contributed to the interpretation of the results from the chart review; Cha MH took lead in the writing of manuscript, with all other authors provided critical feedback that helped finalized the manuscript; Razik R supervised the entire project.
Institutional review board statement: The study was reviewed and approved by the Cleveland Clinic Akron General Institutional Review Board (Approval No. 19007).
Informed consent statement: A waiver of informed consent is granted by the Institutional Review Board at Cleveland Clinic Akron General as this study may not be practicably conducted due to the number of patients lost to follow up and/or expired since the procedure. Please refer to IRB approval letter for further details.
Conflict-of-interest statement: There are no conflict of interest pertaining to this manuscript.
Data sharing statement: Technical appendix, statistical code, and dataset available from the corresponding author at razikr@ccf.org. Consent was not obtained but the presented data are anonymized and risk of identification is low. No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Roshan Razik, FRCPC, MD, MPH, Attending Physician, Department of Gastroenterology, Cleveland Clinic Akron General, 1 Akron General Ave Akron, Akron, OH 44307, United States. razikr@ccf.org
Received: December 4, 2020
Peer-review started: December 4, 2020
First decision: December 18, 2020
Revised: December 31, 2020
Accepted: January 21, 2021
Article in press: January 21, 2021
Published online: February 16, 2021
Abstract
BACKGROUND

Foreign object ingestion (FOI) and food bolus impaction (FBI) are common causes of emergent endoscopic intervention. The choice of sedation used is often dictated by physician experience. Many endoscopists frequently prefer to use monitored anesthesia care (MAC) and general anesthesia (GA) as opposed to conscious sedation (CS) due to the concern for inadequate airway protection. However, there is insufficient data examining the safety of different sedation modalities in emergent endoscopic management of FOI and FBI.

AIM

To investigate the complication rates of emergent endoscopic extraction performed under different sedation modalities.

METHODS

We conducted a retrospective chart review of patients presenting with acute FBI and FOI between 2010 and 2018 in two hospitals. A standardized questionnaire was utilized to collect data on demographics, endoscopic details, sedation practices, hospital stay and adverse events. Complications recognized during and within 24 h of the procedure were considered early, whereas patients presenting with a procedure-related adverse event within two weeks of the index event were considered delayed complications. Complication rates of patients who underwent emergent endoscopic retrieval were compared based on sedation types, namely CS, MAC and GA. Chi-square analysis and multiple logistic regression were used to compare complication rate based on sedation type.

RESULTS

Among the 929 procedures analyzed, 353 procedures (38.0%) were performed under CS, 278 procedures (29.9%) under MAC and the rest (32.1%) under GA. The median age of the subjects was 52 years old, with 57.4% being male. The majority of the procedures (64.3%) were FBI with the rest being FOI (35.7%). A total of 132 subjects (14.2%) had chronic comorbidities while 29.0% had psychiatric disorders. The most commonly observed early complications were mucosal laceration (3.8%) and bleeding (2.6%). The most common delayed complication was aspiration pneumonia (1.8%). A total of 20 patients (5.6%) could not adequately be sedated with CS and had to be converted to MAC or GA. Patient sedated with MAC and GA were more likely to require hospitalization, P < 0.0001. Analysis revealed no statistically significant difference in the complication rate between patients sedated under CS (14.7%), MAC (14.7%) and GA (19.5%), P = 0.19.

CONCLUSION

For patients who present with FOI or FBI and undergo emergent endoscopic treatment, there is no significant difference in adverse event rates between CS, MAC and GA.

Keywords: Foreign body, Food bolus impaction, Endoscopy, Sedation, Anesthesia, Complications

Core Tip: There is insufficient data examining the safety of different sedation modalities in emergent endoscopic management of food bolus impaction or foreign object ingestion. Many endoscopists frequently perform emergent endoscopy under monitored anesthesia care or general anesthesia instead of conscious sedation. This retrospective study aims to investigate the complication rate of emergent endoscopic extraction performed under different sedation modalities. Analysis revealed no significant difference in the complication rate among patients sedated under different sedation modalities. These findings can potentially lead to sedation practices that allow more timely access to emergent endoscopy and further cost savings to the health care system.