Published online Sep 16, 2020. doi: 10.4253/wjge.v12.i9.266
Peer-review started: May 25, 2020
First decision: June 4, 2020
Revised: June 8, 2020
Accepted: August 1, 2020
Article in press: August 1, 2020
Published online: September 16, 2020
Reverse bevel (RB) needle is widely used for endoscopic ultrasound fine needle biopsy (EUS-FNB). A 3-plane symmetrical needle with Franseen geometry (FG) has recently become available.
To compare the clinical efficacy of FG to that of RB needle.
A retrospective cohort study of all adult patients who underwent EUS-FNB for solid and mixed lesions either with 22G RB needle or 22G FG needle between January 2016 and February 2019 was undertaken. All cytology slides were reviewed by an independent gastrointestinal cytopathologist blinded to the needle used and the initial cytology report. The primary and secondary outcomes were to assess the sample adequacy using Euro-cytology criteria and the number of cell clusters, respectively.
Two hundred and twenty six procedures were included in the study. RB needle was used in 128 procedures and FG needle in 98 procedures. The baseline characteristics of both groups were comparable. On multivariable analysis, FG needle (P = 0.02) and location of the lesion (P < 0.01) were independently associated with adequate tissue. Further, the use of FG needle (P = 0.04) and the size of the lesion (P = 0.02) were independently associated with acquisition of increased number of cell clusters.
FG needle is superior to RB needle in acquiring adequate tissue and attaining higher number of cell clusters for solid and mixed lesions.
Core Tip: Despite retrospective, it is the first paper to try to compare the performance of reverse bevel fine needle biopsy (FNB) needle with Franseen geometry FNB needle in term of tissue acquisition and number of cell groups in specimen. Slides reviewed by an independent expert gastrointestinal cytopathologist blinded to needle type used and original cytology reports to minimize bias.