Copyright ©2009 Baishideng. All rights reserved.
World J Gastrointest Endosc. Oct 15, 2009; 1(1): 39-44
Published online Oct 15, 2009. doi: 10.4253/wjge.v1.i1.39
Interventional endoscopic ultrasound: Therapeutic capability and potential
Ilaria Tarantino, Luca Barresi
Ilaria Tarantino, Luca Barresi, Gastroenterology and Endoscopy Department, Medicine University of Pittsburgh Medical Center/Mediterranean Institute for transplantation and Specialized Therapies, Palermo 90127, Italy
Author contributions: Tarantino I analyzed data and wrote the paper; Barresi L reviewed the manuscript.
Correspondence to: Ilaria Tarantino, Assistant professor, Gastroenterology and Endoscopy Department, Medicine University of Pittsburgh Medical Center, via Tricomi 1, Palermo 90100, Italy.
Telephone: +39-91-2192111 Fax: +39-91-2192400
Received: January 16, 2009
Revised: March 9, 2009
Accepted: March 16, 2009
Published online: October 15, 2009

The linear echoendoscope, introduced in the 1990s, opened the era of interventional endoscopic ultrasound (IEUS). The linear echoendoscope enabled EUS guided Fine Needle Aspiration (EUS-FNA) allowing the path of the needle to be traced during the puncture process. After EUS-FNA, other interventional procedures were introduced in clinical practice. Tissue acquisition was the first EUS-guided interventional procedure and its higher diagnostic quality has undoubtedly been established. After EUS-FNA, Celiac plexus neurolysis (CPN) and block (CPB), pancreatic pseudocyst drainage, abdominal and mediastinal collections/abscesses drainage, and in selected cases, pancreatic and biliary ductal system drainage, were introduced in clinical practice. EUS-guided fine needle injection with local delivery of antitumor agents is considered a promising modality. We have reviewed published data on EUS guided interventional procedures with the object of summarizing the diagnostic capability of endoscopic ultrasound and elaborates in detail its therapeutic capability and potential.

Keywords: Endoscopic ultrasound, Interventional endoscopic ultrasound, Endoscopic ultrasound guided fine needle aspiration, Endoscopic ultrasound-guided drainage, Endoscopic ultrasound-fine need injection