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Copyright ©The Author(s) 2015.
World J Hepatol. Aug 18, 2015; 7(17): 2100-2109
Published online Aug 18, 2015. doi: 10.4254/wjh.v7.i17.2100
Table 1 Direct-acting antivirals (clinical development status in parenthesis)
NS3/4A Protease inhibitorsNS5A inhibitorsPolymerase inhibitors
NIsNNIs
Telaprevir (approved)Daclatasvir (approved)Sofosbuvir (approved)Dasabuvir (phase 3)
Boceprevir (approved)Ledipasvir (phase 3)Mericitabine (phase 2)BMS-791325 (phase 3)
Simeprevir (approved)Ombitasvir (approved)VX-135 (phase 2)PPI-383 (phase 1)
Asunaprevir (phase 3)GS-5816 (phase 2)GS-9669 (phase 2)
Danoprevir (phase 3)ACH-2928 (phase 1)TMC647055I (phase 2)
Paritaprevir (approved)ACH-3102 (phase 2)VX-222 (phase 2)
Vaniprevir (phase 3)PPI-668 (phase 2)
Sovaprevir (phase 2)PPI-461 (phase 1)
MK-5172 (phase 3)GSK2336805 (phase 2)
ACH-2684 (phase 2)Samatasvir (phase 2)
Narlaprevir (phase 2)MK-8742 (phase 3)
Vedroprevir (phase 2)BMS-824393 (phase 2)