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World J Hepatol. Aug 18, 2015; 7(17): 2100-2109
Published online Aug 18, 2015. doi: 10.4254/wjh.v7.i17.2100
New treatment strategies for hepatitis C infection
Fatih Ermis, Elif Senocak Tasci
Fatih Ermis, Department of Gastroenterology, Duzce University Faculty of Medicine, 81620 Duzce, Turkey
Elif Senocak Tasci, Department of Internal Medicine, Duzce University Faculty of Medicine, 81620 Duzce, Turkey
Author contributions: Ermis F and Senocak Tasci E contributed equally to this work, generated the tables and figures and wrote the manuscript.
Conflict-of-interest statement: The authors declare that there are no conflicts of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Fatih Ermis, MD, Associate Professor, Department of Gastroenterology, Duzce University Faculty of Medicine, Beciyorukler Street, Konuralp, 81620 Duzce, Turkey. fatihermis2@hotmail.com
Telephone: +90-533-4689404
Received: April 5, 2015
Peer-review started: April 7, 2015
First decision: May 18, 2015
Revised: June 4, 2015
Accepted: July 18, 2015
Article in press: July 22, 2015
Published online: August 18, 2015
Core Tip

Core tip: In this review, we focused on different treatment regimens for hepatitis C infection, especially those including the newly developed and approved direct-acting antivirals. The guidelines are constantly changing in light of new studies. The recommendations of the guidelines are reviewed and consider different genotypes of the virus in addition to the results of ongoing studies. Continuing medical need for agents that act on novel hepatitis C virus targets has resulted in new compounds targeting viral proteins, which is also highlighted in the manuscript.