Original Article
Copyright ©2012 Baishideng Publishing Group Co.
World J Hepatol. Dec 27, 2012; 4(12): 374-381
Published online Dec 27, 2012. doi: 10.4254/wjh.v4.i12.374
Table 1 Comparison of patient characteristics according to B-mode ultrasound-based classification
Type 1(n = 29)Type 2b(n = 43)Type 2c(n = 16)P value
Age (yr)66.4 ± 9.566.9 ± 8.769.3 ± 6.80.554
Gender (male/female)23/625/188/80.085
HCV (positive/negative)28/136/714/20.241
Number of tumors  1.2 ± 0.4  1.2 ± 0.51.6 ± 0.70.046
Size of tumor (mm)22.5 ± 3.819.0 ± 5.223.1 ± 5.60.003
Child-Pugh classification (A/B)16/1331/129/70.272
Tumor stage (I/II/III)10/15/428/13/24/7/50.006
Activity grade (A0, 1/2, 3)7/2214/2910/60.032
Fibrosis stage (F0-2/3, 4)8/2110/337/90.298
AFP (ng/mL) 124 ± 246118 ± 274207 ± 4060.564
AFP-L3 (%)7.3 ± 17.05.8 ± 16.517.5 ± 25.50.098
DCP (mAU/mL) 223 ± 489210 ± 482299 ± 4860.817
Table 2 Univariate analysis of factors contributing to recurrence
VariablesHR95%CIP value
Age (yr)1.0070.972-1.0430.717
Gender
Female1
Male1.0360.577-1.8590.906
HCV
Negative1
Positive1.1760.527-2.6250.693
Number of tumors1.5571.009-2.4040.045
Size of tumor (mm)1.0350.980-1.0920.214
Child-Pugh classification
A1
B1.4810.838-2.6170.177
Tumor stage
I1
II1.2140.657-2.2440.535
III5.0552.123-12.0340.000
Activity grade
A0, 11
A2, 31.3460.745-2.4300.325
Fibrosis stage
F0-21
F3, 41.3230.689-2.5400.401
AFP (ng/mL)1.0001.000-1.0010.318
AFP-L3 (%)1.0171.004-1.0300.023
DCP (mAU/mL)1.0001.000-1.0010.332
B-mode classification
Type 2b1
Type 11.5310.767-3.0530.227
Type 2c3.1791.623-6.2270.001
Table 3 Multivariate analysis of factors contributing to recurrence
VariablesHR95%CIP value
n1.4110.719-2.7700.317
Tumor stage
I1
II0.6450.283-1.4670.296
III2.5400.784-8.2240.120
AFP-L3
Negative1
Positive1.5310.642-3.6490.337
B-mode classification
Type 2b1
Type 11.8500.878-3.8990.106
Type 2c2.4381.107-5.3730.027
Table 4 Univariate analysis of factors contributing to survival
VariablesHR95%CIP value
Age (yr)0.9790.929-1.0320.440
Gender
Female1
Male1.1610.435-3.0960.766
HCV
Negative1
Positive0.9470.218-4.1240.943
Number of tumors1.7000.840-3.4400.140
Size of tumor (mm)1.0300.945-1.1230.504
Child-Pugh classification
A1
B1.7890.710-4.5120.218
Tumor stage
I1
II1.5880.551-4.5790.392
III3.8471.081-13.6900.037
Activity grade
A0, 11
A2, 31.9780.698-5.6060.200
Fibrosis stage
F0-21
F3, 41.2920.425-3.9300.652
AFP (ng/mL)1.0011.000-1.0020.087
AFP-L3 (%)1.0120.995-1.0310.212
DCP (mAU/mL)1.0000.999-1.0010.919
B-mode classification
Type 2b1
Type 16.9111.897-25.1760.003
Type 2c4.4661.066-18.7090.041
Table 5 Multivariate analysis of factors contributing to survival
VariablesHR95%CIP value
Tumor stage
I1
II1.1890.406-3.4810.752
III3.7630.896-15.7960.070
B-mode classification
Type 2b1
Type 17.1461.924-26.5380.003
Type 2c3.0550.668-13.9700.150