Editorial
Copyright ©The Author(s) 2022.
World J Hepatol. Jul 27, 2022; 14(7): 1269-1276
Published online Jul 27, 2022. doi: 10.4254/wjh.v14.i7.1269
Table 1 Pros and cons on the indication for liver biopsy in clinical practice
Benefits
Limitations
To rule out pre-existing liver diseasesInvasiveness
To confirm diagnosis (i.e.; granulomas)Cost
Differentiate anti-PD1/PD-L1 from anti-CTLA4- induced DILIPathognomic histological features are lacking
To establish the severity of liver injury.Unclear influence on patient management
To discriminate ICIs-induced DILI from typical seronegative classical AIHBiochemical features might be sufficient
To assess a possible chronicity evolution