Body mass index and its effects on liver fat content in overweight and obese young adults by proton magnetic resonance spectroscopy technique

Table 1 Characteristic and biochemical analysis of 78 subjects in the control and overweight/obese groups

	Control group	OW/OB group	P-value	Correlation with LFC
				r	P value
n	39	39	-	-	-
Gender (male/female)	12/27	24/15	-	-	-
LFC (%)	2.7 ± 0.2	8.1 ± 1.0	< 0.001b	-	-
Age	22.3 ± 1.6	22.1 ± 0.3	0.662	-0.058	0.611
BMI (kg/m2)	20.9 ± 0.3	31.3 ± 0.5	< 0.001b	0.531	< 0.001b
WC (cm)	74.6 ± 1.4	112.6 ± 7.4	< 0.001b	0.259	0.022a
HC (cm)	90.7 ± 1.3	122.5 ± 7.5	< 0.001b	0.212	0.062
W/H ratio	0.8 ± 0.0	0.9 ± 0.0	< 0.001b	0.388	< 0.001b
FG (mg/dL)	83.1 ± 1.1	89.9 ± 1.1	< 0.001b	0.144	0.21
Cho (mg/dL)	187.3 ± 6.8	200.7 ± 6.1	0.147	0.093	0.419
Tri (mg/dL)	77.8 ± 5.2	117.1 ± 8.8	< 0.001b	0.223	0.05
HDL (mg/dL)	59.3 ± 2.5	47.7 ± 1.4	< 0.001b	-0.185	0.105
LDL (mg/dL)	111.1 ± 5.6	130.1 ± 5.1	0.014a	0.133	0.246
HbA1c (%)	5.1 ± 0.1	5.5 ± 0.1	< 0.001b	0.345	0.002a

Data expressed as mean ± SD.

^aP < 0.05;

^bP < 0.001. OW/OB: Overweight/obese; LFC: Liver fat content; BMI: Body mass index; WC: Waist circumference; HC: Hip circumference; W/H ratio: Waist-to-hip ratio; FG: Fasting plasma glucose; Cho: Cholesterol; Tri: Triglyceride; HDL: High-density lipoproteins; LDL: Low-density lipoproteins; HbA1c: Glycosylated hemoglobin.

Table 2 Multiple linear regression analysis showing relationship of blood biochemical marker and anthropometry marker with LFC as the dependent variable

	Model 1			Model 2			Model 3
	R2	β(SE)	P	R2	β(SE)	P	R2	β(SE)	P
HbA1c	0.135	0.306	0.002	0.174	0.339	0.004	0.298	0.120	0.327
		(1.273)			(1.283)			(1.379)
Tri		0.131	0.247		0.065	0.590		-0.029	0.590
		(0.012)			(0.013)			(0.012)
BMI	0.295	0.463	< 0.001a	0.299	0.459	< 0.001a
		(0.109)			(0.111)
WC		-0.026	0.824		-0.034	0.774
		(0.016)			(0.017)
W/H ratio		0.145	0.247		0.136	0.288
		(8.768)			(9.018)

Model 1 is unadjusted model. Model 2 is Model 1 adjusted for sex and age. Model 3 is Model 2 adjust for body mass index. Statistical significance:

^aP < 0.001. β: Standardized coefficient; SE: Estimated error; R²: Correction coefficient; LFC: Liver fat content; HbA1c: Glycosylated hemoglobin; Tri: Triglyceride; BMI: Body mass index; WC: Waist circumference; W/H ratio: Waist-to-hip ratio.