Phase angle obtained by bioelectrical impedance analysis independently predicts mortality in patients with cirrhosis
Giliane Belarmino, Raquel S Torrinhas, Priscila Sala, Wellington Andraus, Luiz Augusto Carneiro D’Albuquerque, Graziela R Ravacci, Dan L Waitzberg, Department of Gastroenterology, Surgical Division, Faculdade de Medicina da Universidade de São Paulo, Sao Paulo 05403-000, Brazil
Maria Cristina Gonzalez, Postgraduate Program in Health and Behavior, Universidade Católica de Pelotas, Pelotas 96015-560, Brazil
Maria Cristina Gonzalez, Steven B Heymsfield, Pennington Biomedical Research Center, Baton Rouge, LA 70808, United States
Rosa Maria R Pereira, Valéria F Caparbo, Laboratory of Bone Metabolism, Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, São Paulo 05403-000, Brazil
Lucas Damiani, Research Institute, Hospital do Coração de São Paulo, São Paulo 04004-030, Brazil
Author contributions: Belarmino G, Gonzalez MC, Waitzberg DL, Heymsfield SB, Pereira RMR and D’Albuquerque LAC contributed to the conception and design and/or coordination of the study; Belarmino G, Gonzalez MC, Torrinhas RS, Waitzberg DL, Sala P, Andraus W, Heymsfield SB and Caparbo VF were responsible for the acquisition, analysis, and/or interpretation and discussion of data; Belarmino G, Torrinhas RS, Gonzalez MC and Ravacci GR drafted the manuscript; Damiani L performed statistical analyses; all authors read and approved the final manuscript.
Supported by The Fundação de Amparo à Pesquisa do Estado de São Paulo, Nos. 2011/13243-3, 2012/15677-3 [GB].
Institutional review board statement: The study was reviewed and approved by the Institutional Ethics Review Board (0646/11) of the Hospital das Clínicas (São Paulo, SP, Brazil).
Clinical trial registration statement: This clinical trial was registered at ClinicalTrials.gov with the identifier NCT02421848. Details can be found at https://clinicaltrials.gov/ct2/show/NCT02421848.
Informed consent statement: All study participants, or their legal guardians, provided written consent prior to study enrollment.
Conflict-of-interest statement: The authors of this manuscript have no conflict of interest to disclose.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Dr. Giliane Belarmino, Department of Gastroenterology, Surgical Division, Faculdade de Medicina da Universidade de São Paulo, Avenida Dr. Arnaldo, 455, Cerqueira César, Sao Paulo 05403-000, Brazil. email@example.com
Telephone: +55-11-30617459 Fax: +55-11-30617459
Received: July 30, 2016
Peer-review started: August 2, 2016
First decision: September 8, 2016
Revised: December 22, 2016
Accepted: January 11, 2017
Article in press: January 14, 2017
Published online: March 8, 2017