Published online Sep 8, 2017. doi: 10.4254/wjh.v9.i25.1054
Peer-review started: February 8, 2017
First decision: June 12, 2017
Revised: August 6, 2017
Accepted: August 15, 2017
Article in press: August 16, 2017
Published online: September 8, 2017
Core tip: Though decreasing, hepatitis B still remains a considerable problem, especially in high-risk patient populations as kidney transplant recipients. The widespread use of new antivirals and the introduction of universal prophylaxis immediately after transplantation have changed the picture in hepatitis B virus (HBV) (+) transplantation. Long term survival rates of HBV(+) recipients are approaching those of HBV(-), altering HBV(+) kidney transplantation from a “high risk” procedure into routine practice. Furthermore, accumulating evidence confirms the safety of transplantation from HBsAg(+) donors into immunized recipients. All immunosuppressants can be used in HBV(+) transplantation and total immunosuppression must be kept at the lowest possible levels long term.