Published online Aug 18, 2017. doi: 10.4254/wjh.v9.i23.990
Peer-review started: January 18, 2017
First decision: May 9, 2017
Revised: May 20, 2017
Accepted: June 12, 2017
Article in press: June 13, 2017
Published online: August 18, 2017
Core tip: Everolimus is the most recently approved immunosuppressant for use in liver transplantation (LT). Its renoprotective effect is an attractive option for LT recipients who have calcineurin inhibitor-induced nephrotoxicity. This review examines through data published, discovers gaps of evidences and discusses the place in therapy for everolimus (EVR) in LT. At the end of review, it summarises how EVR can benefit LT recipients as well as the caveat in using EVR.