Efficacy and safety of dual therapy with daclatasvir and asunaprevir in elderly patients
Kazuo Tarao, Tarao’s Gastroenterological Clinic, Yokohama 241-0821, Japan
Katsuaki Tanaka, Akito Nozaki, Gastroenterological Center, Medical Center, Yokohama City University, Yokohama 232-0024, Japan
Akira Sato, Toshiya Ishii, Division of Gastroenterology, Department of Internal Medicine, St. Marianna University, Yokohama City Seibu Hospital, Yokohama 241-0811, Japan
Hirokazu Komatsu, Department of Gastroenterology, Yokohama Municipal Citizen’s Hospital, Yokohama 240-8555, Japan
Takaaki Ikeda, Department of Gastroenterology, Yokosuka General Hospital Uwamachi, Yokosuka 238-8567, Japan
Tatsuji Komatsu, Shozo Matsushima, Department of Clinical Research, National Hospital Organization, Yokohama Medical Center, Yokohama 245-8575, Japan
Kenji Oshige, Yokohama National University, Center for Health Service Sciences, Yokohama 240-8501, Japan
Author contributions: Tarao K designed the research; Tanaka K, Nozaki A, Ishii T, Komatsu H, Ikeda T, Komatsu T and Matsushima S followed up the HCV patients in field practice; Oshige K analyzed the data; Tarao K wrote the paper; all the descriptions of the paper were distributed to all authors and confirmed.
Institutional review board statement: The study was approved by institutional review boards in each hospital and conducted in compliance with the Declaration of Helsinki.
Informed consent statement: Written informed consent was obtained from all patients.
Conflict-of-interest statement: Tanaka K has received research funding from Bristol-Myers Squibb and AbbVie; Nozaki A has received research funding from Gilead Sciences; Tarao K, Sato A, Ishii T, Komatsu H, Ikeda T, Komatsu T, Matsushima S and Oshige K declare that have no conflict of interest.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Kazuo Tarao, MD, Tarao’s Gastroenterological Clinic, Taiyo-Building, 2-58-6, Futamatagawa, Asahi-ku, Yokohama 241-0821, Japan. firstname.lastname@example.org
Telephone: +81-45-3606501 Fax: +81-45-3606502
Received: October 18, 2016
Peer-review started: October 23, 2016
First decision: December 20, 2016
Revised: January 19, 2017
Accepted: February 8, 2017
Article in press: February 13, 2017
Published online: April 18, 2017