Retrospective Cohort Study
Copyright ©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Hepatol. Dec 28, 2016; 8(36): 1617-1622
Published online Dec 28, 2016. doi: 10.4254/wjh.v8.i36.1617
Spontaneous bacterial peritonitis prevalence in pre-transplant patients and its effect on survival and graft loss post-transplant
Neeral L Shah, Nicolas M Intagliata, Zachary H Henry, Curtis K Argo, Patrick G Northup
Neeral L Shah, Nicolas M Intagliata, Zachary H Henry, Curtis K Argo, Patrick G Northup, Division of Gastroenterology and Hepatology, Department of Medicine, University of Virginia, Charlottesville, VA 22908, United States
Author contributions: Shah NL and Northup PG and performed designed research; Northup PG analyzed data; Shah NL, Intagliata NM, Henry ZH, Argo CK and Northup PG wrote the paper.
Institutional review board statement: Study approved by IRB at University of Virginia.
Informed consent statement: A cohort study on a de-identified population did not require consent.
Conflict-of-interest statement: We have no conflicts of interest to report.
Data sharing statement: No additional data is available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Neeral L Shah, MD, Division of Gastroenterology and Hepatology, Department of Medicine, University of Virginia, Jefferson Park Avenue, PO Box 800708, Charlottesville, VA 22908, United States. neeral.shah@virginia.edu
Telephone: +1-434-9242626 Fax: +1-434-2447586
Received: June 28, 2016
Peer-review started: June 30, 2016
First decision: August 5, 2016
Revised: October 25, 2016
Accepted: November 16, 2016
Article in press: November 17, 2016
Published online: December 28, 2016
Core Tip

Core tip: Prevention of spontaneous bacterial peritonitis (SBP) pre-transplant may affect graft outcomes and ultimately patient survival post-transplant. Patients with hepatitis C virus (HCV) in whom therapy is deferred until the time of transplant due to hepatic decompensation, may benefit from expedited treatment if they possess a history of SBP to avoid complications related to HCV recurrence.