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©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Hepatitis C virus infection and thyroid autoimmune disorders: A model of interactions between the host and the environment
Francesca Pastore, Antonio Martocchia, Manuela Stefanelli, Pietro Prunas, Stefania Giordano, Lavinia Toussan, Antonio Devito, Paolo Falaschi, “Sapienza” University of Rome, Faculty of Medicine and Psychology, S. Andrea Hospital, 00189 Rome, Italy
Author contributions: All authors contributed to the manuscript.
Conflict-of-interest statement: No financial conflicts of interest or other relationships are present in the manuscript.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Francesca Pastore, MD, “Sapienza” University of Rome, Faculty of Medicine and Psychology, S. Andrea Hospital, Via di Grottarossa 1035/39, 00189 Rome, Italy. francesca.past@virgilio.it
Telephone: +39-6-33775467 Fax: +39-6-33775401
Received: April 28, 2015
Peer-review started: May 6, 2015
First decision: October 14, 2015
Revised: October 28, 2015
Accepted: December 3, 2015
Article in press: December 4, 2015
Published online: January 18, 2016
Peer-review started: May 6, 2015
First decision: October 14, 2015
Revised: October 28, 2015
Accepted: December 3, 2015
Article in press: December 4, 2015
Published online: January 18, 2016
Core Tip
Core tip: This review examines the relationship between the hepatitis C virus (HCV) infection and the thyroid autoimmunity, on the basis of recent evidence of the literature about the mechanisms of self tolerance and thyroid damage related to HCV. The advances in the HCV infection treatment have been discussed in the paper, with relevant clinical results.