Copyright
©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Hepatol. May 28, 2015; 7(9): 1157-1167
Published online May 28, 2015. doi: 10.4254/wjh.v7.i9.1157
Published online May 28, 2015. doi: 10.4254/wjh.v7.i9.1157
Hepatocellular carcinoma: Advances in diagnosis, management, and long term outcome
Adam S Bodzin, Ronald W Busuttil, Department of Surgery, University of California, Los Angeles, CA 90095, United States
Author contributions: Bodzin AS and Busuttil RW contributed to this paper.
Conflict-of-interest: None of the authors have received fees for serving as a speaker or consultant, nor have they received research funding in relation to this manuscript or its research.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Ronald W Busuttil, MD, PhD, Distinguished Professor and Executive Chairman, Department of Surgery, University of California, 757 Westwood Plaza, Suite 8236, Los Angeles, CA 90095, United States. rbusuttil@mednet.ucla.edu
Telephone: +1-310-2678054 Fax: +1-310-2673668
Received: October 22, 2014
Peer-review started: October 22, 2014
First decision: November 27, 2014
Revised: December 13, 2014
Accepted: March 4, 2015
Article in press: March 5, 2015
Published online: May 28, 2015
Peer-review started: October 22, 2014
First decision: November 27, 2014
Revised: December 13, 2014
Accepted: March 4, 2015
Article in press: March 5, 2015
Published online: May 28, 2015
Core Tip
Core tip: Hepatocellular carcinoma (HCC) is a growing malignancy with poor survival. New therapies for the hepatitis C virus may help prevent the development of this malignancy, however the growing obesity epidemic will continue to foster new cases of HCC. With the aid of advances in imaging patients might be diagnosed earlier making them candidates for curative resection or transplantation. In addition, with a growing population of patients undergoing surgery after being down-staged with locoregional therapy, we expect an improvement in long-term outcomes for HCC patients.