Published online Apr 18, 2015. doi: 10.4254/wjh.v7.i5.738
Peer-review started: August 20, 2014
First decision: September 16, 2014
Revised: December 9, 2014
Accepted: January 15, 2015
Article in press: January 19, 2015
Published online: April 18, 2015
Core tip: Transarterial radioembolization (TARE) is a consolidated therapy for hepatocellular carcinoma. TARE is best indicated for both intermediate-stage patients (according to the Barcelona clinic liver cancer staging classification) who have lesions which respond poorly to chemoembolization due to multiple tumors or large tumor burden, and for locally advanced-stage patients with solitary tumors, and segmental or lobar portal vein tumor thrombosis. Moreover, emerging data have suggested the use of TARE in patients who are classified slightly beyond the Milan criteria regarding radical treatment for downstaging purposes. This review analyzes the best selection criteria for patients who really benefit from TARE.