Published online Apr 8, 2015. doi: 10.4254/wjh.v7.i4.688
Peer-review started: August 29, 2014
First decision: October 14, 2014
Revised: November 11, 2014
Accepted: January 9, 2015
Article in press: January 12, 2015
Published online: April 8, 2015
Core tip: Recently a pathophysiological classification of cirrhosis has been strongly encouraged. Hepatic venous pressure gradient (HVPG) measurement is the most reliable tool to estimate the severity of portal hypertension in cirrhosis but several methodological concerns have limited its use in clinical practice. The article summarizes the results published about the prognostic value of HVPG and originally offers a critical revision of the information provided by this hemodynamic parameter on top of the most widely used models based on non-hemodynamic parameters.