Published online Dec 28, 2015. doi: 10.4254/wjh.v7.i30.2962
Peer-review started: June 26, 2015
First decision: September 8, 2015
Revised: September 25, 2015
Accepted: December 17, 2015
Article in press: December 18, 2015
Published online: December 28, 2015
Core tip: Lifestyle modification with diet and exercise remain the mainstay of therapy for nonalcoholic fatty liver disease. Loss of at least 7%-10% of body weight with limiting high fructose corn syrup and high-saturated/high glycemic index foods should be combined with regular, vigorous physical activity. The future of treatment will continue to evolve and likely include the role of anti fibrotic agents, surgical management and transplantation when indicated.