Topic Highlight
Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Hepatol. Dec 28, 2015; 7(30): 2962-2967
Published online Dec 28, 2015. doi: 10.4254/wjh.v7.i30.2962
Management of non-alcoholic fatty liver disease in 2015
Neel Malhotra, Melanie D Beaton
Neel Malhotra, Melanie D Beaton, Department of Medicine, Division of Gastroenterology, Western University, London, ON N6A 3A5, Canada
Melanie D Beaton, London Health Sciences Centre, University Hospital, London, ON N6A 5A5, Canada
Author contributions: Malhotra N and Beaton MD analyzed the literature and wrote the manuscript.
Conflict-of-interest statement: The authors have no conflict of interest to report.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Correspondence to: Dr. Melanie D Beaton, London Health Sciences Centre, University Hospital, Room A10-223, 339 Windermere Road, London, ON N6A 5A5, Canada.
Telephone: +1-519-6633344 Fax: +1-519-6633220
Received: June 25, 2015
Peer-review started: June 26, 2015
First decision: September 8, 2015
Revised: September 25, 2015
Accepted: December 17, 2015
Article in press: December 18, 2015
Published online: December 28, 2015
Core Tip

Core tip: Lifestyle modification with diet and exercise remain the mainstay of therapy for nonalcoholic fatty liver disease. Loss of at least 7%-10% of body weight with limiting high fructose corn syrup and high-saturated/high glycemic index foods should be combined with regular, vigorous physical activity. The future of treatment will continue to evolve and likely include the role of anti fibrotic agents, surgical management and transplantation when indicated.