Published online Mar 27, 2015. doi: 10.4254/wjh.v7.i3.616
Peer-review started: August 26, 2014
First decision: September 19, 2014
Revised: October 1, 2014
Accepted: December 3, 2014
Article in press: December 3, 2014
Published online: March 27, 2015
Core tip: The present review describes the evidence-based consensus on the diagnosis, prevention and management of hepatitis C virus (HCV) disease. Besides the conventional techniques more advanced technologies have come to the front that provides best detection with greater ease and specificity. It is of immense importance to prevent this infection among the sexual partners, injecting drug users, mother-to-infant transmission of HCV, household contact, healthcare workers and people who get tattoos and piercing on their skin. Management includes examining the treatment, assessment of hepatic condition before commencing therapy, controlling the parameters upon which dual and triple therapies work, monitoring after treatment and adjusting the co-factors.