Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Hepatol. Mar 27, 2015; 7(3): 600-606
Published online Mar 27, 2015. doi: 10.4254/wjh.v7.i3.600
Occult hepatitis B virus infection and blood transfusion
Dong Hee Seo, Dong Hee Whang, Eun Young Song, Kyou Sup Han
Dong Hee Seo, Labgenomics Clinical Laboratories, Seongnam-si 463-400, South Korea
Dong Hee Whang, Department of Laboratory Medicine, Inje University College of Medicine, Seoul Paik Hospital, Seoul 100-032, South Korea
Eun Young Song, Kyou Sup Han, Department of Laboratory Medicine, Seoul National University College of Medicine, Seoul 110-744, South Korea
Author contributions: All authors contributed to this paper.
Conflict-of-interest: There are no conflicts of interests.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Correspondence to: Dong Hee Seo, MD, PhD, Labgenomics Clinical Laboratories, B-6F, 700, Daewangpangyo-ro, Bundang-gu, Seongnam-si 463-400, Gyeonggi-do, South Korea.
Telephone: +82-31-6280730 Fax: +82-31-6280701
Received: August 23, 2014
Peer-review started: August 24, 2014
First decision: November 3, 2014
Revised: November 29, 2014
Accepted: December 16, 2014
Article in press: December 16, 2014
Published online: March 27, 2015
Core Tip

Core tip: Hepatitis B surface antigen negative but hepatitis B virus (HBV) DNA positive blood products can evoke hepatitis in blood recipients. Anti-hepatitis B core and HBV nucleic acid testing screening tests are necessary to prevent occult HBV infection transmission by transfusion. Anti-HBs antibody in donors and recipients can protect against hepatitis B infection.