Variations and mutations in the hepatitis B virus genome and their associations with clinical characteristics
Yoshihiko Yano, Takeshi Azuma, Department of Gastroenterology, Kobe University Graduate School of Medicine, Kusunoki-cho, Kobe 650-0017, Japan
Yoshihiko Yano, Yoshitake Hayashi, Center for Infectious Diseases, Kobe University Graduate School of Medicine, Kusunoki-cho, Kobe 650-0017, Japan
Author contributions: Yano Y mainly contributed to this review; Azuma T and Hayashi Y contributed to critical revision and finalized the manuscript.
Supported by A Grant-in-Aid from the Japan Initiative for Global Research Network on Infectious Disease (J-GRID) Program of the Ministry of Education, Culture, Sports, Science and Technology, Japan; a SATREPS Grant from the Japan Science and Technology Agency and the Japan International Cooperation Agency; and by the Ministry of Health, Labour, and Welfare of Japan, No. H25-general-008.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Dr. Yoshihiko Yano, MD, PhD, Center for Infectious Diseases, Graduate School of Medicine, Kobe University, 7-5-1 Kusunoki-cho, Chuo-Ku, Kobe 650-0017, Japan. email@example.com
Telephone: +81-78-3826305 Fax: +81-78-3826309
Received: August 28, 2014
Peer-review started: August 28, 2014
First decision: November 14, 2014
Revised: November 27, 2014
Accepted: December 29, 2014
Article in press: December 29, 2014
Published online: March 27, 2015