Published online Mar 27, 2015. doi: 10.4254/wjh.v7.i3.392
Peer-review started: September 9, 2014
First decision: November 14, 2014
Revised: December 10, 2014
Accepted: January 9, 2015
Article in press: January 9, 2015
Published online: March 27, 2015
Core tip: The investigation and management of pediatric cirrhosis presents several challenges. The etiology of the condition may vary according to patient age. In many cases, cirrhosis is a predictable consequence of the progression of several chronic liver diseases, such as biliary atresia, although it may also be detected when splenomegaly is discovered on routine examination, or during the investigation of conditions such as hypersplenism, anemia, thrombocytopenia, leukopenia, petechiae and/or ecchymosis. The present article will discuss the diagnostic and treatment aspects of cirrhosis in children and adolescents.