Published online Mar 27, 2015. doi: 10.4254/wjh.v7.i3.315
Peer-review started: August 28, 2014
First decision: September 18, 2014
Revised: November 27, 2014
Accepted: December 16, 2014
Article in press: December 16, 2014
Published online: March 27, 2015
Core tip: The review focuses on the multiple physio-pathogenetic aspects of the possible link between psoriasis and non-alcoholic fatty liver disease (NAFLD) emphasizing the most recent scientific data. The importance of the multidisciplinary approach to patients affected by psoriasis is underlined and the therapeutic options to treat concomitant psoriasis and NAFLD is discussed evaluating the risk benefit of both biologic and non-biologic therapies.