Published online Sep 8, 2015. doi: 10.4254/wjh.v7.i19.2214
Peer-review started: January 30, 2015
First decision: March 20, 2015
Revised: April 13, 2015
Accepted: August 30, 2015
Article in press: August 31, 2015
Published online: September 8, 2015
Core tip: Chronic hepatitis C is associated with significant morbidity and mortality, as a result of the progression towards cirrhosis and hepatocellular carcinoma. Furthermore, hepatitis C virus seems to be an independent risk factor for cardiovascular diseases due to its association with insulin resistance, diabetes and steatosis. The advent of new direct acting antiviral therapy has dramatically increased the sustained virological response rates of hepatitis C infection. In this scenario, the cardiovascular risk has emerged and represents a major concern after achieving the eradication of the virus.