Case Report
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World J Hepatol. Jul 27, 2014; 6(7): 527-531
Published online Jul 27, 2014. doi: 10.4254/wjh.v6.i7.527
Acute fatty liver of pregnancy associated with severe acute pancreatitis: A case report
Cássio Vieira de Oliveira, Alecsandro Moreira, Julio P Baima, Leticia de C Franzoni, Talles B Lima, Fabio da S Yamashiro, Kunie Yabuki Rabelo Coelho, Ligia Y Sassaki, Carlos Antonio Caramori, Fernando G Romeiro, Giovanni F Silva
Cássio Vieira de Oliveira, Alecsandro Moreira, Julio P Baima, Leticia de C Franzoni, Talles B Lima, Fabio da S Yamashiro, Ligia Y Sassaki, Carlos Antonio Caramori, Fernando G Romeiro, Giovanni F Silva, Department of Internal Medicine, Gastroenterology Division, Botucatu Medical School, São Paulo State University-UNESP, Botucatu, São Paulo 01049-010, Brazil
Kunie Yabuki Rabelo Coelho, Department of Pathology, Botucatu Medical School, São Paulo State University-UNESP, Botucatu, São Paulo 01049-010, Brazil
Author contributions: de Oliveira CV conceived and coordinated the study and participated in the data acquisition and manuscript writing; Lima TB, Baima J, Coelho KYR, Sassaki LY, Caramori CA, Moreira A and Silva GF participated in the data acquisition and manuscript writing; Romeiro FG coordinated the study and participated in the data acquisition and manuscript writing; Coelho KYR coordinated the histopathological analysis.
Supported by The Department of Internal Medicine, Gastroenterology Division, Botucatu Medical School, São Paulo State University-UNESP, Botucatu/SP, Brazil
Correspondence to: Cássio Vieira de Oliveira, PhD, Department of Internal Medicine, Gastroenterology Division, Botucatu Medical School, São Paulo State University-UNESP, Rua Quirino de Andrade, 215, Botucatu, São Paulo 01049-010, Brazil. cassiovieira01@hotmail.com
Telephone: +55-14-997624920 Fax: +55-14-38116213
Received: March 12, 2014
Revised: May 20, 2014
Accepted: June 10, 2014
Published online: July 27, 2014
Core Tip

Core tip: A previously healthy 26-year-old woman at 27 wk and 6 d of pregnancy was referred for investigation of abdominal pain. She presented with complaints of diffuse abdominal pain with nausea and vomiting associated with hepatic and renal dysfunction. Acute fatty liver of pregnancy and severe acute pancreatitis were diagnosed. Acute fatty liver of pregnancy is rarely associated with severe acute pancreatitis, which can complicate the diagnosis. The possible mechanisms involved in this association and the current therapies are discussed, focusing on the relevant aspects to improve the management of similar cases.