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World J Hepatol. May 27, 2014; 6(5): 306-314
Published online May 27, 2014. doi: 10.4254/wjh.v6.i5.306
Published online May 27, 2014. doi: 10.4254/wjh.v6.i5.306
Metabolic syndrome and non-alcoholic fatty liver disease in liver surgery: The new scourges?
François Cauchy, David Fuks, Jacques Belghiti, Service de Chirurgie Hépato-Bilio-Pancréatique et Transplantation Hépatique, Hôpital Beaujon, Assistance Publique - Hôpitaux de Paris, 92110 Clichy, France
Alban Zarzavadjian Le Bian, Laboratoire de Recherche en Ethique Médicale et Médecine Légale, Université de Paris 5 Descartes, 75006 Paris, France
Renato Costi, Dipartimento di Scienze Chirurgiche, Università degli Studi di Parma, Azienda Ospedaliero-Universitaria di Parma, 43100 Parma, Italy
Author contributions: Cauchy F and Costi R designed the research; Cauchy F and Fuks D performed the research; Cauchy F, Fuks D and Zarzavadjian Le Bian A analyzed the data; Cauchy F wrote the paper; Fuks D, Zarzavadjian Le Bian A, Belghiti J and Costi R gave an important intellectual contribution; Belghiti J and Costi R supervised.
Correspondence to: Renato Costi, MD, PhD, FACS, Dipartimento di Scienze Chirurgiche, Università degli Studi di Parma, Azienda Ospedaliero-Universitaria di Parma, Via Gramsci 14, 43100 Parma, Italy. renatocosti@hotmail.com
Telephone: +39-335-8234285 Fax: +39-521-940125
Received: November 9, 2013
Revised: January 1, 2014
Accepted: January 17, 2014
Published online: May 27, 2014
Revised: January 1, 2014
Accepted: January 17, 2014
Published online: May 27, 2014
Core Tip
Core tip: The metabolic syndrome (MS) and its hepatic manifestations, non-alcoholic fatty liver disease (NAFLD), are increasingly observed in Western countries. Both MS and NAFLD could favor the development of primary liver malignancies and may also lead to end-stage liver disease. These patients are at higher operative risk because of underestimated postoperative liver related complications but also specific increase in cardio-vascular complications. Specific improvements in the perioperative management of these patients are required in order to improve the operative results.