Anti-oxidative stress treatment and current clinical trials

doi:10.4254/wjh.v16.i2.294

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World Journal of Hepatology

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1948-5182

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Letter to the Editor

World J Hepatol. Feb 27, 2024; 16(2): 294-299
Published online Feb 27, 2024. doi: 10.4254/wjh.v16.i2.294

Anti-oxidative stress treatment and current clinical trials

Chun-Ye Zhang, Ming Yang

Chun-Ye Zhang, Bond Life Sciences Center, University of Missouri, Columbia, MO 65211, United States

Ming Yang, Department of Surgery, University of Missouri, Columbia, MO 65212, United States

Author contributions: Zhang CY and Yang M designed the study, collected the data, and wrote, revised, and finalized the manuscript.

Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.

Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

Corresponding author: Ming Yang, DVM, PhD, Research Assistant Professor, Department of Surgery, University of Missouri, 1030 Hitt Street, Columbia, MO 65212, United States. yangmin@health.missouri.edu

Received: November 2, 2023
Peer-review started: November 2, 2023
First decision: December 27, 2023
Revised: January 8, 2024
Accepted: February 5, 2024
Article in press: February 5, 2024
Published online: February 27, 2024

Core Tip

Core Tip: Oxidative stress disturbs the balance between the production and detoxification of reactive oxygen species, which is implicated in many diseases. Therefore, anti-oxidative stress agents have been widely explored to treat chronic and metabolic diseases. In this letter, we further discuss the current clinical trials related to anti-oxidative stress treatment and summarize current medicines under investigation.