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World J Hepatol. Oct 27, 2022; 14(10): 1875-1883
Published online Oct 27, 2022. doi: 10.4254/wjh.v14.i10.1875
Alcohol use disorder and liver injury related to the COVID-19 pandemic
Giuseppe Marano, Gianandrea Traversi, Eleonora Gaetani, Roberto Pola, Angelo Emilio Claro, Marianna Mazza
Giuseppe Marano, Angelo Emilio Claro, Marianna Mazza, Department of Geriatrics, Neuroscience and Orthopedics, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Rome 00168, Italy
Gianandrea Traversi, Dipartimento di Medicina di Laboratorio, UOSD Genetica Medica, Ospedale Generale “San Giovanni Calibita” Fatebenefratelli, Rome 00186, Italy
Eleonora Gaetani, Department of Medical and Surgical Sciences, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Rome 00168, Italy
Roberto Pola, Division of Internal Medicine, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Rome 00168, Italy
Author contributions: Mazza M and Marano G designed the study and wrote the first draft of the manuscript; Traversi G, Gaetani E, Pola R, and Claro AE supervised and added important contributions to the paper; All authors have read and agreed to the published version of the manuscript.
Conflict-of-interest statement: Authors declare no conflict of interests for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Marianna Mazza, MD, PhD, Assistant Professor, Department of Geriatrics, Neuroscience and Orthopedics, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Largo A. Gemelli 8, Rome 00168, Italy. mariannamazza@hotmail.com
Received: August 21, 2022
Peer-review started: August 21, 2022
First decision: September 8, 2022
Revised: September 26, 2022
Accepted: October 10, 2022
Article in press: October 10, 2022
Published online: October 27, 2022
Core Tip

Core Tip: Alcohol use disorder is a complex phenomenon with psychological and physical consequences. Alcohol-associated liver disease is a devastating complication of alcohol use disorder. Following the spread of coronavirus disease 2019 (COVID-19) and consequent lockdown there was an increase in alcohol consumption resulting in a worrying increase in steatosis of the liver, alcohol-related steato-hepatitis and alcohol-related liver disease. In addition, patients with alcohol-associated liver disease may be more susceptible to COVID-19 and a worse prognosis. This review focuses on the emergence of alcohol-induced liver damage as a major medical and social problem during the COVID-19 pandemic.