Copyright
©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
High omega arachidonic acid/docosahexaenoic acid ratio induces mitochondrial dysfunction and altered lipid metabolism in human hepatoma cells
Reem Ghazali, Kosha J Mehta, SW Annie Bligh, Ihab Tewfik, Dahn Clemens, Vinood B Patel
Reem Ghazali, SW Annie Bligh, Ihab Tewfik, Vinood B Patel, School of Life Sciences, University of Westminster, London W1W 6UW, United Kingdom
Reem Ghazali, Clinical Biochemistry Department, Faculty of medicine, King Abdulaziz University, Jeddah 21589, Saudi Arabia
Kosha J Mehta, Centre for Education, Faculty of Life Sciences and Medicine, King's College London SE1 1UL, United Kingdom
SW Annie Bligh, Caritas Institute of Higher Education, Hong Kong 999077, China
Dahn Clemens, Nebraska and Western Iowa Veterans Administration Medical Center and Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE 68198, United States
Author contributions: Ghazali R was the primary researcher, collected and analyzed data; Mehta K wrote the manuscript, analyzed data, prepared figures and formatted manuscript for publication; Bligh A provided intellectual input and feedback on manuscript; Tewfik I provided intellectual input and feedback on manuscript; Clemens D provided intellectual input and feedback on manuscript; Patel V conceived, designed and directed the study, analyzed data and approved the article to be published.
Conflict-of-interest statement: The authors declare no conflict of interest.
Data sharing statement: All authors have reviewed and approved the data.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Vinood B Patel, FRSC, PhD, Reader (Associate Professor), School of Life Sciences, University of Westminster, 115 New Cavendish Street, London W1W 6UW, United Kingdom. v.b.patel@westminster.ac.uk
Received: July 14, 2019
Peer-review started: July 16, 2019
First decision: November 2, 2019
Revised: December 24, 2019
Accepted: January 14, 2020
Article in press: January 14, 2020
Published online: March 27, 2020
