Retrospective Study
Copyright ©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Hepatol. Aug 27, 2019; 11(8): 638-645
Published online Aug 27, 2019. doi: 10.4254/wjh.v11.i8.638
Impact of psychosocial comorbidities on clinical outcomes after liver transplantation: Stratification of a high-risk population
Neil Bhogal, Amaninder Dhaliwal, Elizabeth Lyden, Fedja Rochling, Marco Olivera-Martinez
Neil Bhogal, Amaninder Dhaliwal, Fedja Rochling, Marco Olivera-Martinez, Department of Internal Medicine, Division of Gastroenterology and Hepatology, University of Nebraska Medical Center, Omaha, NE 68198, United States
Elizabeth Lyden, Department of Biostatistics, Division of Public Health, University of Nebraska Medical Center, Omaha, NE 68198, United States
Author contributions: Bhogal N contributed to study formulation, study design, data compilation, data analysis, and manuscript preparation; Dhaliwal A contributed to study formulation, study design, data analysis, and manuscript preparation; Lyden E contributed to study design and statistical analysis; Rochling F contributed to data analysis and manuscript preparation; Olivera-Martinez M contributed to study formulation, study design, data analysis, and manuscript preparation.
Institutional review board statement: This study was reviewed and approved by the University of Nebraska Institutional Review Board No. 304-17-EP.
Conflict-of-interest statement: No potential conflicts of interest relevant to this article were reported.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Neil Bhogal, Department of Internal Medicine, Division of Gastroenterology and Hepatology, University of Nebraska Medical Center, 982000 NMC, Omaha, NE 68198, United States. neil.bhogal@unmc.edu
Telephone: +1-661-4969737
Received: March 20, 2019
Peer-review started: March 20, 2019
First decision: April 23, 2019
Revised: May 23, 2019
Accepted: July 16, 2019
Article in press: July 17, 2019
Published online: August 27, 2019
Core Tip

Core tip: As there is a limited number of organs available for transplantation, a successful outcome depends upon a complete evaluation. There is a paucity of data regarding the impact of psychosocial comorbidities and their impact after liver transplantation. Our study found that patients with certain psychosocial comorbidities had worse outcomes after liver transplantation. This work adds to the growing literature that this represents a high-risk population.