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Copyright ©The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Hepatol. Jul 27, 2018; 10(7): 485-495
Published online Jul 27, 2018. doi: 10.4254/wjh.v10.i7.485
Balloon-occluded transcatheter arterial chemoembolization for hepatocellular carcinoma
Takeshi Hatanaka, Hirotaka Arai, Satoru Kakizaki
Takeshi Hatanaka, Department of Gastroenterology, Saiseikai Maebashi Hospital, Gunma 371-0821, Japan
Hirotaka Arai, Department of Gastroenterology, Maebashi Red Cross Hospital, Gunma 371-0014, Japan
Satoru Kakizaki, Department of Gastroenterology and Hepatology, Gunma University Graduate School of Medicine, Gunma 371-8511, Japan
Author contributions: All authors have contributed to the study concept, data analyzing, manuscript writing, editing and approval of the final manuscript for publication.
Conflict-of-interest statement: No potential conflicts of interest. No financial support.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Satoru Kakizaki, MD, PhD, Associate Professor, Department of Gastroenterology and Hepatology, Gunma University Graduate School of Medicine, Showa-machi, 3-39-15, Maebashi, Gunma 371-8511, Japan. kakizaki@gunma-u.ac.jp
Telephone: +81-27-2208127 Fax: +81-27-2208136
Received: March 27, 2018
Peer-review started: March 27, 2018
First decision: April 11, 2018
Revised: June 24, 2018
Accepted: June 28, 2018
Article in press: June 28, 2018
Published online: July 27, 2018
Core Tip

Core tip: Balloon-occluded transcatheter arterial chemoembolization (B-TACE) was recently developed in Japan. Despite the lack of a clear definition, B-TACE is generally defined as the infusion of emulsion of chemotherapeutic agents with lipiodol followed by gelatin particles under the occlusion of feeding arteries by a microballoon catheter. Although randomized controlled trials comparing the therapeutic effect and the prognosis of B-TACE to those of the other TACE procedures are still lacking, B-TACE is thought to be a promising treatment. The purpose of this review is to summarize the mechanism, therapeutic effect, indication, prognosis and complications of B-TACE.