Copyright ©The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Hepatol. Jul 27, 2018; 10(7): 462-473
Published online Jul 27, 2018. doi: 10.4254/wjh.v10.i7.462
MR with Gd-EOB-DTPA in assessment of liver nodules in cirrhotic patients
Riccardo Inchingolo, Riccardo Faletti, Luigi Grazioli, Eleonora Tricarico, Marco Gatti, Anna Pecorelli, Davide Ippolito
Riccardo Inchingolo, Eleonora Tricarico, Division of Interventional Radiology, Department of Radiology, Madonna delle Grazie Hospital, Matera 75100, Italy
Riccardo Faletti, Marco Gatti, Department of Surgical Sciences, Radiology Unit, University of Turin, Turin 10126, Italy
Luigi Grazioli, Department of Radiology, University of Brescia “Spedali Civili”, Brescia 25123, Italy
Anna Pecorelli, Davide Ippolito, Department of Diagnostic Radiology, School of Medicine, University of Milano-Bicocca, Monza 20900, Italy
Author contributions: All authors equally contributed to this paper with conception and design of the study, literature review and analysis, drafting and critical revision and editing, and final approval of the final version.
Conflict-of-interest statement: All the authors are aware of the content of the manuscript and have no conflict of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Correspondence to: Riccardo Inchingolo, MD, Doctor, Division of Interventional Radiology, Department of Radiology, Madonna delle Grazie Hospital, Via Montescaglioso, Matera 75100, Italy.
Telephone: +39-333-4601735 Fax: +39-835-253857
Received: March 26, 2018
Peer-review started: March 27, 2018
First decision: April 18, 2018
Revised: April 25, 2018
Accepted: May 30, 2018
Article in press: May 30, 2018
Published online: July 27, 2018
Core Tip

Core tip: Hepatobiliary contrast agents improve detection and characterization of focal liver lesions in patients with cirrhotic liver. Gd-EOB-DTPA provides information not only on vascular changes but also on hepatocyte function. Based on the recent advances in liver magnetic resonance imaging (MRI) technology, in this review, we discuss the pivotal role of Gd-EOB-DTPA enhanced MRI for the future of hepatocellular carcinoma’s management.