Published online Oct 27, 2020. doi: 10.4254/wjh.v12.i10.816
Peer-review started: May 25, 2020
First decision: June 12, 2020
Revised: June 26, 2020
Accepted: August 16, 2020
Article in press: August 16, 2020
Published online: October 27, 2020
In Mexico, the epidemiology of pyogenic liver abscess (PLA) is unknown, with some small case series. This study recruited patients from two high-level hospitals in Mexico.
PLA is a rare medical condition that has had a change in its etiology in recent years; however, more studies are needed to determine the epidemiology of PLA in Mexico.
The aim of this study was to describe the current clinical, demographic, and microbiologic characteristics of PLAs in two high-volume centers in Mexico. These data will allow us to understand the behavior of this disease in Mexico.
This is a retrospective analysis of patients with PLA from two high-level hospitals in Mexico. A chart review was performed to evaluate the clinical, demographic and microbiologic characteristics of PLA. A multivariate analysis was performed to identify independent risk factors associated with mortality.
The main isolated microorganisms were ESBL-Escherichia coli and Klebsiella pneumoniae. The inpatient mortality rate was 63%. In multivariate analysis, immunocompromised state, ESBL-Escherichia coli, and Klebsiella pneumoniae were independent predictors of high risk mortality
An increased prevalence in both referral centers has been noted. The mortality rate was significantly higher compared to previously reported rates worldwide, reaching 63%. There was a steady shift to a predominant Klebsiella pneumoniae-related abscess.
As a retrospective review, our study is limited. Prospective studies that monitor the mortality rate are required, which in this study was high compared to that reported in other series.