Published online Jan 27, 2018. doi: 10.4254/wjh.v10.i1.166
Peer-review started: September 15, 2017
First decision: October 31, 2017
Revised: November 6, 2017
Accepted: December 28, 2017
Article in press: December 28, 2017
Published online: January 27, 2018
A 72-year-old man visited our institution due to the onset of abdominal pain.
Computed tomography (CT) and magnetic resonance (MR) images revealed a liver tumor.
Hepatocellular carcinoma and another type of malignant tumor of the liver.
Laboratory tests demonstrated liver enzyme elevation. Alpha-fetoprotein, des-gamma-carboxy prothrombin, carcinoembryonic antigen and carbohydrate antigen were within normal range.
Gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid-enhanced (Gd-EOB-DTPA -enhanced) MR imaging revealed a liver tumor that showed slight hyperintensity in the hepatobiliary phase.
Atypical endothelial cells had regularly infiltrated into the sinusoid and replaced sinusoidal cells in a broad range of hepatic parenchyma; as a result, hepatic cell cords remained in the tumor. Pathological findings were consistent with hepatic angiosarcoma.
After admission, the patient experienced worsening liver and renal failure. He died from multiple organ failure nine days after admission.
Hepatic angiosarcoma has various appearances on CT and MR images, but contrast uptake in primary hepatic angiosarcoma on Gd-EOB-DTPA-enhanced MR imaging in the hepatobiliary phase has not been reported.
There are no non-standard terms used in this manuscript.
The authors present this case to share important knowledge for hepatic angiosarcoma diagnosis.