Copyright ©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Hepatol. Aug 28, 2017; 9(24): 1013-1021
Published online Aug 28, 2017. doi: 10.4254/wjh.v9.i24.1013
Role of endoscopic ultrasound in liver disease: Where do we stand in 2017?
Hamzeh A Saraireh, Mohammad Bilal, Shailendra Singh
Hamzeh A Saraireh, Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX 77555, United States
Mohammad Bilal, Division of Gastroenterology and Hepatology, University of Texas Medical Branch, Galveston, TX 77555, United States
Shailendra Singh, Division of Gastroenterology, Hepatology and Nutrition, Allegheny General Hospital, Pittsburgh, PA 15212, United States
Author contributions: Saraireh HA and Bilal M performed literature review and search; Saraireh HA wrote the initial manuscript which was edited by Bilal M; Bilal M wrote certain parts of the manuscript; Singh S was involved in editing the manuscript and provided expert opinion.
Conflict-of-interest statement: The authors report no conflict of interest and have no financial disclosures.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Correspondence to: Shailendra Singh, MD, Division of Gastroenterology, Hepatology and Nutrition, Allegheny General Hospital, 320 East North Avenue, Pittsburgh, PA 15212, United States.
Telephone: +1-412-2775244 Fax: +1-412-3598439
Received: April 7, 2017
Peer-review started: April 10, 2017
First decision: May 19, 2017
Revised: June 11, 2017
Accepted: July 21, 2017
Article in press: July 24, 2017
Published online: August 28, 2017

Endoscopic ultrasound (EUS) was first introduced into medical practice in 1980s as a diagnostic imaging modality for pancreatic pathology. EUS has the unique advantage of combining ultrasound and endoscopy to obtain detailed information of the gastrointestinal tract. Over the past decade, the use of EUS in liver diseases has been increasing. EUS, which was initially used as a diagnostic tool, is now having increasing therapeutic role as well. We provide a review of the application of EUS in the diagnostic and therapeutic aspects of liver disease. We also look at the evolving future research on the role of EUS in liver diseases.

Keywords: Endoscopic ultrasound, Liver disease, Portal hypertension, Liver lesions

Core tip: We have summarized the up-to-date literature on the emerging role of endoscopic ultrasound (EUS) in liver disease. This brief review summarizes both the diagnostic and therapeutic role of EUS in focal hepatic lesions, portal hypertension, liver abscess and hepatic cysts. We have also summarized the future research on this subject.