Priadko K, Niosi M, Vitale LM, De Sio C, Romano M, De Sio I. “Starry liver” - Von Meyenburg complex clinical case presentation and differential diagnosis discussion: A case report. World J Hepatol 2022; 14(7): 1520-1527 [PMID: 36158921 DOI: 10.4254/wjh.v14.i7.1520]
Corresponding Author of This Article
Kateryna Priadko, MD, Academic Research, Department of Precision Medicine and Hepato-Gastroenterology Unit, University Hospital and Università degli Studi della Campania Luigi Vanvitelli, Piazza Miraglia 2, Naples 80138, Italy. kateryna.priadko@unicampania.it
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Hepatol. Jul 27, 2022; 14(7): 1520-1527 Published online Jul 27, 2022. doi: 10.4254/wjh.v14.i7.1520
“Starry liver” - Von Meyenburg complex clinical case presentation and differential diagnosis discussion: A case report
Kateryna Priadko, Marco Niosi, Luigi Maria Vitale, Chiara De Sio, Marco Romano, Ilario De Sio
Kateryna Priadko, Marco Niosi, Luigi Maria Vitale, Marco Romano, Ilario De Sio, Department of Precision Medicine and Hepato-Gastroenterology Unit, University Hospital and Università degli Studi della Campania Luigi Vanvitelli, Naples 80138, Italy
Chiara De Sio, Internal Medicine Unit, Camilliani Hospital, Casoria 80026, Italy
Author contributions: De Sio I, Vitale LM, Niosi M, and De Sio C performed and interpreted the imaging findings and managed the patient; Priadko K reviewed the literature and drafted the manuscript; De Sio I contributed to manuscript drafting; Romano M was responsible for the revision and final approval of the manuscript; all authors issued final approval for the version to be submitted.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: All authors have no conflicts of interest to declare.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Kateryna Priadko, MD, Academic Research, Department of Precision Medicine and Hepato-Gastroenterology Unit, University Hospital and Università degli Studi della Campania Luigi Vanvitelli, Piazza Miraglia 2, Naples 80138, Italy. kateryna.priadko@unicampania.it
Received: April 4, 2022 Peer-review started: April 4, 2022 First decision: April 28, 2022 Revised: May 29, 2022 Accepted: June 13, 2022 Article in press: June 13, 2022 Published online: July 27, 2022
Abstract
BACKGROUND
Von Meyenburg complex (VMC) (i.e., biliary hamartoma) is a rare congenital disorder characterized by multiple dilated cystic bile ducts, without clear trends in sex or age predominance. Due to the low number of published cases and the lack of recognized guidelines, the management of such patients remains a clinical challenge.
CASE SUMMARY
We present a case of symptomatic VMC that was diagnosed after imaging and histopathological examinations. Considering the patient’s condition, a conservative treatment strategy was chosen. Instrumental, laboratory, and clinical follow-up demonstrated the stable condition of the patient receiving conservative treatment.
CONCLUSION
VMC is a potentially non-life threatening condition, but its recognition is crucial for the management of patients.
Core Tip: Von Meyenburg complex (VMC) is a congenital bile duct malformation, which is asymptomatic and non-life threatening in most cases. As such, it remains underdiagnosed. Here, we report the features of VMC detected in a symptomatic patient by contrast-enhanced ultrasonography and magnetic resonance imaging. The prescribed treatment gradually improved the patient’s condition. Throughout the surveillance period, the patient remained asymptomatic. In reporting this case study, we highlight the need for thorough differential diagnosis of VMC as well as a personalized treatment approach that considers disease complications, if present.
