Published online Nov 27, 2022. doi: 10.4254/wjh.v14.i11.1920
Peer-review started: August 17, 2022
First decision: September 26, 2022
Revised: October 10, 2022
Accepted: November 16, 2022
Article in press: November 16, 2022
Published online: November 27, 2022
Liver is an organ having extremely diversified functions, ranging from metabolic and synthetic to detoxification of harmful chemicals. The multifunctionality of the liver in principle requires the multidisciplinary and pluralistic interventions for its management. Several studies have investigated liver function, dysfunction and clinic. This editorial work discusses new ideas, challenges and perspectives of current research regarding multidisciplinary and pluralistic management of liver diseases. In one hand the discussions have carried out on the involvement of extracellular vesicles, Na+/H+ exchangers, severe acute respiratory syndrome coronavirus 2 and Epstein–Barr virus infections, Drug-induced liver injury, sepsis, pregnancy, and food supplements in hepatic disorders. In the other hand this study has discussed hepatocellular carcinoma algorithms and new bio
Core Tip: This study uses an open multidisciplinary citation analysis database based on artificial intelligence technology to deal with multidisciplinary and pluralistic approaches of liver diseases management, providing a useful and practical tool for physician and scholars.