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For: Lanthier N. Targeting Kupffer cells in non-alcoholic fatty liver disease/non-alcoholic steatohepatitis: Why and how? World J Hepatol 2015; 7(19): 2184-2188 [PMID: 26380042 DOI: 10.4254/wjh.v7.i19.2184]
URL: https://www.wjgnet.com/1948-5182/full/v7/i19/2184.htm
Number Citing Articles
1
Nicolas Lanthier, Peter Stärkel. Treatment of severe alcoholic hepatitis: past, present and future. European Journal of Clinical Investigation 2017; 47(7) doi: 10.1111/eci.12767
2
Yichao Hou, Xilong Gao, Jiahui Gong, Xinrui Dong, Yanling Hao, Zhengyuan Zhai, Hao Zhang, Ming Zhang, Rong Liu, Ran Wang, Liang Zhao. Targeted Sodium Acetate Liposomes for Hepatocytes and Kupffer Cells: An Oral Dual-Targeted Therapeutic Approach for Non-Alcoholic Fatty Liver Disease Alleviation. Nutrients 2025; 17(5) doi: 10.3390/nu17050930
3
Q Binet, A Loumaye, V Preumont, J-P Thissen, M.P. Hermans, N Lanthier. Non-invasive screening, staging and management of metabolic dysfunction-associated fatty liver disease (MAFLD) in type 2 diabetes mellitus patients : what do we know so far ?. Acta Gastro Enterologica Belgica 2022; 85(2) doi: 10.51821/85.2.9775
4
Quentin Etienne, Valérie Lebrun, Mina Komuta, Benoît Navez, Jean-Paul Thissen, Isabelle A. Leclercq, Nicolas Lanthier. Fetuin-A in Activated Liver Macrophages Is a Key Feature of Non-Alcoholic Steatohepatitis. Metabolites 2022; 12(7) doi: 10.3390/metabo12070625
5
Mengzhen Li, Faren Xie, Lu Wang, Guoxue Zhu, Lian-Wen Qi, Shujun Jiang. Celastrol: An Update on Its Hepatoprotective Properties and the Linked Molecular Mechanisms. Frontiers in Pharmacology 2022; 13 doi: 10.3389/fphar.2022.857956
6
Jun Ho Lee, Hana Song, Eun Jin Yoo, Yeseul Jeong, Seung Mi Ko, Go Woon Shin, Gee Euhn Choi, Youngheun Jee, Minhyeok Kang, Jiwon Yang, Sung-Pyo Hur, Jong-Eun Park, Yunkyoung Lee, Hye-Kyung Park, Ji-Hyun Yun, Mi-Kyoung Jang, Whaseon Lee-Kwon, Hyug Moo Kwon, Soo Youn Choi. Hepatocyte TonEBP promotes metabolic stress-induced hepatic fibroinflammation involving transcriptional activation of ELR⁺ CXC chemokines. Cell Death Discovery 2026; 12(1) doi: 10.1038/s41420-026-02978-3
7
Jorge Gutiérrez-Cuevas, Arturo Santos, Juan Armendariz-Borunda. Pathophysiological Molecular Mechanisms of Obesity: A Link between MAFLD and NASH with Cardiovascular Diseases. International Journal of Molecular Sciences 2021; 22(21) doi: 10.3390/ijms222111629
8
Lawan Rabiu, Pengchao Zhang, Lukman O. Afolabi, Muhammad A. Saliu, Salisu M. Dabai, Rabiatu B. Suleiman, Khalid I. Gidado, Mark A. Ige, Abdulrahman Ibrahim, Guizhong Zhang, Xiaochun Wan. Immunological dynamics in MASH: from landscape analysis to therapeutic intervention. Journal of Gastroenterology 2024; 59(12) doi: 10.1007/s00535-024-02157-0
9
10
Nicolas Lanthier, Valérie Lebrun, Olivier Molendi-Coste, Nico van Rooijen, Isabelle A. Leclercq. Liver Fetuin-A at Initiation of Insulin Resistance. Metabolites 2022; 12(11) doi: 10.3390/metabo12111023
11
Anna Alisi, Guido Carpino, Felipe L. Oliveira, Nadia Panera, Valerio Nobili, Eugenio Gaudio. The Role of Tissue Macrophage-Mediated Inflammation on NAFLD Pathogenesis and Its Clinical Implications. Mediators of Inflammation 2017; 2017 doi: 10.1155/2017/8162421
12
Farah D.R. Al-Baiaty, Aziana Ismail, Zarina Abdul Latiff, Khairul Najmi Muhammad Nawawi, Raja Affendi Raja Ali, Norfilza Mohd Mokhtar. Possible Hepatoprotective Effect of Tocotrienol-Rich Fraction Vitamin E in Non-alcoholic Fatty Liver Disease in Obese Children and Adolescents. Frontiers in Pediatrics 2021; 9 doi: 10.3389/fped.2021.667247
13
Alessandra Caligiuri, Alessandra Gentilini, Fabio Marra. Molecular Pathogenesis of NASH. International Journal of Molecular Sciences 2016; 17(9) doi: 10.3390/ijms17091575
14
Lampros Chrysavgis, Ilias Giannakodimos, Panagiota Diamantopoulou, Evangelos Cholongitas. Non-alcoholic fatty liver disease and hepatocellular carcinoma: Clinical challenges of an intriguing link. World Journal of Gastroenterology 2022; 28(3): 310-331 doi: 10.3748/wjg.v28.i3.310
15
Lisanne L. Blauw, Zhuang Li, Sander S. Rensen, Jan Willem M. Greve, Aswin Verhoeven, Rico J. Derks, Martin Giera, Yanan Wang, Patrick C.N. Rensen. Metabolic liver inflammation in obesity does not robustly decrease hepatic and circulating CETP. Atherosclerosis 2018; 275 doi: 10.1016/j.atherosclerosis.2018.06.004
16
17
Takashi Yamaguchi, Katsunori Yoshida, Miki Murata, Kanehiko Suwa, Koichi Tsuneyama, Koichi Matsuzaki, Makoto Naganuma. Smad3 Phospho-Isoform Signaling in Nonalcoholic Steatohepatitis. International Journal of Molecular Sciences 2022; 23(11) doi: 10.3390/ijms23116270
18
Frédéric Clarembeau, Georgia Bale, Nicolas Lanthier. Cirrhosis and insulin resistance: current knowledge, pathophysiological mechanisms, complications and potential treatments. Clinical Science 2020; 134(16) doi: 10.1042/CS20200022
19
Kyoko Tomita, Rohit Kohli, Brittany L. MacLaurin, Petra Hirsova, Qianqian Guo, Luz H. Gutierrez Sanchez, Harris A. Gelbard, Burns C. Blaxall, Samar H. Ibrahim. Mixed-lineage kinase 3 pharmacological inhibition attenuates murine nonalcoholic steatohepatitis. JCI Insight 2017; 2(15) doi: 10.1172/jci.insight.94488
20
Samar H Ibrahim, Petra Hirsova, Gregory J Gores. Non-alcoholic steatohepatitis pathogenesis: sublethal hepatocyte injury as a driver of liver inflammation. Gut 2018; 67(5) doi: 10.1136/gutjnl-2017-315691
21
Juan Du, Xuemei Cao, Junlin Diao, Qijuan Zhang, Chuan Peng, Jibin Li, Xiaoqiu Xiao. Neonatal overfeeding in mice aggravates the development of methionine and choline-deficient diet-induced steatohepatitis in adulthood. Genes & Diseases 2019; 6(1) doi: 10.1016/j.gendis.2017.12.008
22
Guoqiang Fan, Yanfei Li, Jinglong Chen, Yibo Zong, Xiaojing Yang. DHA/AA alleviates LPS-induced Kupffer cells pyroptosis via GPR120 interaction with NLRP3 to inhibit inflammasome complexes assembly. Cell Death & Disease 2021; 12(1) doi: 10.1038/s41419-020-03347-3
23
Kyoko Tomita, Brittany L. Freeman, Steven F. Bronk, Nathan K. LeBrasseur, Thomas A. White, Petra Hirsova, Samar H. Ibrahim. CXCL10-Mediates Macrophage, but not Other Innate Immune Cells-Associated Inflammation in Murine Nonalcoholic Steatohepatitis. Scientific Reports 2016; 6(1) doi: 10.1038/srep28786
24
Martí Ortega-Ribera, Mrigya Babuta, Gyongyi Szabo. Sinusoidal Cells in Liver Diseases. 2024;  doi: 10.1016/B978-0-323-95262-0.00002-4
25
Haiou Li, Yunjiao Zhou, Haizhou Wang, Meng Zhang, Peishan Qiu, Mengna Zhang, Ruike Zhang, Qiu Zhao, Jing Liu. Crosstalk Between Liver Macrophages and Surrounding Cells in Nonalcoholic Steatohepatitis. Frontiers in Immunology 2020; 11 doi: 10.3389/fimmu.2020.01169
26
Elizabeth C. Stahl, Evan R. Delgado, Frances Alencastro, Samuel T. LoPresti, Patrick D. Wilkinson, Nairita Roy, Martin J. Haschak, Clint D. Skillen, Satdarshan P. Monga, Andrew W. Duncan, Bryan N. Brown. Inflammation and Ectopic Fat Deposition in the Aging Murine Liver Is Influenced by CCR2. The American Journal of Pathology 2020; 190(2) doi: 10.1016/j.ajpath.2019.10.016
27
Marie Lequoy, Elia Gigante, Jean-Pierre Couty, Christèle Desbois-Mouthon. Hepatocellular carcinoma in the context of non-alcoholic steatohepatitis (NASH): recent advances in the pathogenic mechanisms. Hormone Molecular Biology and Clinical Investigation 2020; 41(1) doi: 10.1515/hmbci-2019-0044
28
29
Rishi Sharma, Kevin Liaw, Anjali Sharma, Ambar Jimenez, Michelle Chang, Sebastian Salazar, Imaan Amlani, Sujatha Kannan, Rangaramanujam M. Kannan. Glycosylation of PAMAM dendrimers significantly improves tumor macrophage targeting and specificity in glioblastoma. Journal of Controlled Release 2021; 337 doi: 10.1016/j.jconrel.2021.07.018
30
Xiaoyan Zhang, Jingxin Li, Tiancai Liu, Min Zhao, Baozhu Liang, Hong Chen, Zhen Zhang, Ihtisham Bukhari. Identification of Key Biomarkers and Immune Infiltration in Liver Tissue after Bariatric Surgery. Disease Markers 2022; 2022 doi: 10.1155/2022/4369329
31
Dae Won Ma, Joohun Ha, Kyung Sik Yoon, Insug Kang, Tae Gyu Choi, Sung Soo Kim. Innate Immune System in the Pathogenesis of Non-Alcoholic Fatty Liver Disease. Nutrients 2023; 15(9) doi: 10.3390/nu15092068
32
Dinali H. Fernando, Josephine M. Forbes, Peter W. Angus, Chandana B. Herath. Development and Progression of Non-Alcoholic Fatty Liver Disease: The Role of Advanced Glycation End Products. International Journal of Molecular Sciences 2019; 20(20) doi: 10.3390/ijms20205037
33
Niranjani Venkateswaran, Scott Weismiller, Karen Krok. Recurrent NASH Post-liver Transplant: Implications and Treatment. Current Hepatology Reports 2021; 20(4) doi: 10.1007/s11901-021-00569-7
34
Nicolas Lanthier. Dynamic imaging of macrophages in MASLD: A major interest in insulin resistance and outside the liver. JHEP Reports 2025; 7(5) doi: 10.1016/j.jhepr.2025.101352
35
Mehmet Sayiner, Brian Lam, Pegah Golabi, Zobair M. Younossi. Advances and challenges in the management of advanced fibrosis in nonalcoholic steatohepatitis. Therapeutic Advances in Gastroenterology 2018; 11 doi: 10.1177/1756284818811508
36
Linlin Yao, Yuanyuan Wang, Jianbo Shi, Yanna Liu, Hao Guo, Xiaoxi Yang, Yaquan Liu, Junjie Ma, Danyang Li, Ziniu Wang, Zikang Li, Qian Luo, Jianjie Fu, Qinghua Zhang, Guangbo Qu, Yanxin Wang, Guibin Jiang. Toxicity of Tetrabromobisphenol A and Its Derivative in the Mouse Liver Following Oral Exposure at Environmentally Relevant Levels. Environmental Science & Technology 2021; 55(12) doi: 10.1021/acs.est.1c01726
37
38
Marco Arrese, Daniel Cabrera, Alexis M. Kalergis, Ariel E. Feldstein. Innate Immunity and Inflammation in NAFLD/NASH. Digestive Diseases and Sciences 2016; 61(5) doi: 10.1007/s10620-016-4049-x
39
Nicolas Lanthier, Nathalie Lin-Marq, Laura Rubbia-Brandt, Sophie Clément, Nicolas Goossens, Laurent Spahr. Autologous bone marrow-derived cell transplantation in decompensated alcoholic liver disease: what is the impact on liver histology and gene expression patterns?. Stem Cell Research & Therapy 2017; 8(1) doi: 10.1186/s13287-017-0541-2
40
Sine Kragh Petersen, Orsolya Bilkei‐Gorzo, Olivier Govaere, Anetta Härtlova. Macrophages and scavenger receptors in obesity‐associated non‐alcoholic liver fatty disease (NAFLD). Scandinavian Journal of Immunology 2020; 92(5) doi: 10.1111/sji.12971
41
Chi Ma, Qianfei Zhang, Tim F. Greten. Nonalcoholic fatty liver disease promotes hepatocellular carcinoma through direct and indirect effects on hepatocytes. The FEBS Journal 2018; 285(4) doi: 10.1111/febs.14209
42
Zixiong Zhou, Jong Won Kim, Jing Zhao, Jing Qi, Seong Jin Choi, Chae Woong Lim, Moo-Yeol Lee, Kyuhong Lee, Bumseok Kim. Treatment of cigarette smoke extract and condensate differentially potentiates palmitic acid-induced lipotoxicity and steatohepatitis in vitro. Toxicology in Vitro 2018; 52 doi: 10.1016/j.tiv.2018.05.017
43
Antonio Sircana, Elena Paschetta, Francesca Saba, Federica Molinaro, Giovanni Musso. Recent Insight into the Role of Fibrosis in Nonalcoholic Steatohepatitis-Related Hepatocellular Carcinoma. International Journal of Molecular Sciences 2019; 20(7) doi: 10.3390/ijms20071745
44
Daryl Ramai, Waqqas Tai, Michelle Rivera, Antonio Facciorusso, Nicola Tartaglia, Mario Pacilli, Antonio Ambrosi, Christian Cotsoglou, Rodolfo Sacco. Natural Progression of Non-Alcoholic Steatohepatitis to Hepatocellular Carcinoma. Biomedicines 2021; 9(2) doi: 10.3390/biomedicines9020184
45
Juan Zheng, Ting Chen, Xin Guo, James M. Ntambi, Chaodong Wu. Lipid Signaling and Metabolism. 2020;  doi: 10.1016/B978-0-12-819404-1.00014-2
46
Liyun Xu, Wen Liu, Fuxiang Bai, Yong Xu, Xiaohong Liang, Chunhong Ma, Lifen Gao. Hepatic Macrophage as a Key Player in Fatty Liver Disease. Frontiers in Immunology 2021; 12 doi: 10.3389/fimmu.2021.708978
47
Nicolas Lanthier, Nathalie Delzenne. Targeting the Gut Microbiome to Treat Metabolic Dysfunction-Associated Fatty Liver Disease: Ready for Prime Time?. Cells 2022; 11(17) doi: 10.3390/cells11172718
48
Komal Sodhi, Krithika Srikanthan, Perrine Goguet-Rubio, Alexandra Nichols, Amrita Mallick, Athar Nawab, Rebecca Martin, Preeya T. Shah, Muhammad Chaudhry, Saroj Sigdel, Mehiar El-Hamdani, Jiang Liu, Zijian Xie, Nader G. Abraham, Joseph I. Shapiro. RETRACTED ARTICLE: pNaKtide Attenuates Steatohepatitis and Atherosclerosis by Blocking Na/K-ATPase/ROS Amplification in C57Bl6 and ApoE Knockout Mice Fed a Western Diet. Scientific Reports 2017; 7(1) doi: 10.1038/s41598-017-00306-5
49
Ozlem Kutlu, Humeyra Nur Kaleli, Ebru Ozer. Molecular Pathogenesis of Nonalcoholic Steatohepatitis- (NASH-) Related Hepatocellular Carcinoma. Canadian Journal of Gastroenterology and Hepatology 2018; 2018 doi: 10.1155/2018/8543763
50
Cheng Ma, Cheng Wang, Yafang Zhang, Honglin Zhou, Yunxia Li. Potential Natural Compounds for the Prevention and Treatment of Nonalcoholic Fatty Liver Disease: A Review on Molecular Mechanisms. Current Molecular Pharmacology 2022; 15(6) doi: 10.2174/1874467215666211217120448
51
Zhenjun Yu, Mengdie Chen, Shicheng Gu, Chaohui Wang, Ping Feng, Gang Lin. Sugar-sweetened beverage consumption predicts metabolic associated fatty liver disease in patients with type 2 diabetes mellitus. Frontiers in Endocrinology 2025; 16 doi: 10.3389/fendo.2025.1651370
52
Zhongbo Liu, Jose Cordoba-Chacon, Rhonda D. Kineman, Bruce N. Cronstein, Radhika Muzumdar, Zhenwei Gong, Haim Werner, Shoshana Yakar. Growth Hormone Control of Hepatic Lipid Metabolism. Diabetes 2016; 65(12) doi: 10.2337/db16-0649
53
Quentin M. Anstee, Helen L. Reeves, Elena Kotsiliti, Olivier Govaere, Mathias Heikenwalder. From NASH to HCC: current concepts and future challenges. Nature Reviews Gastroenterology & Hepatology 2019; 16(7) doi: 10.1038/s41575-019-0145-7
54
Sébastien Lepreux, Julien Villeneuve, Antoine Dewitte, Annie M. Bérard, Alexis Desmoulière, Jean Ripoche. CD40 signaling and hepatic steatosis: Unanticipated links. Clinics and Research in Hepatology and Gastroenterology 2017; 41(4) doi: 10.1016/j.clinre.2016.11.002
55
Xue-Kai Wang, Zong-Gen Peng. Targeting Liver Sinusoidal Endothelial Cells: An Attractive Therapeutic Strategy to Control Inflammation in Nonalcoholic Fatty Liver Disease. Frontiers in Pharmacology 2021; 12 doi: 10.3389/fphar.2021.655557
56
Lindsey Devisscher, Xavier Verhelst, Isabelle Colle, Hans Van Vlierberghe, Anja Geerts. The role of macrophages in obesity-driven chronic liver disease. Journal of Leukocyte Biology 2016; 99(5) doi: 10.1189/jlb.5RU0116-016R
57
Helk Oliver, Dekeryte Ruta, Dawn Thompson, Sarah Kamli-Salino, Sam Philip, Heather M. Wilson, Nimesh Mody, Mirela Delibegovic. Myeloid PTP1B deficiency protects against atherosclerosis by improving cholesterol homeostasis through an AMPK-dependent mechanism. Journal of Translational Medicine 2023; 21(1) doi: 10.1186/s12967-023-04598-2
58
Guoqiang Fan, Yanfei Li, Yaxin Liu, Xiaoyi Suo, Yimin Jia, Xiaojing Yang. Gondoic acid alleviates LPS‑induced Kupffer cells inflammation by inhibiting ROS production and PKCθ/ERK/STAT3 signaling pathway. International Immunopharmacology 2022; 111 doi: 10.1016/j.intimp.2022.109171
59
Moumita Saha, Krishnendu Manna, Krishna Das Saha. Melatonin Suppresses NLRP3 Inflammasome Activation via TLR4/NF-κB and P2X7R Signaling in High-Fat Diet-Induced Murine NASH Model. Journal of Inflammation Research 2022;  doi: 10.2147/JIR.S343236