Copyright ©The Author(s) 2020.
World J Stem Cells. May 26, 2020; 12(5): 339-350
Published online May 26, 2020. doi: 10.4252/wjsc.v12.i5.339
Table 1 Clinical trials employing mesenchymal stem cells for bone healing
Allogeneic mesenchymal stem cell transplantation in tibial closed diaphyseal fracturesTibial fractureMesenchymal stem cell injection240Completed
The efficacy of mesenchymal stem cells for stimulating the union in treatment of non-united tibial and femoral fractures in Shahid Kamyab HospitalNonunion fractureInjection of mesenchymal stem cell in non-union site219Completed
Bone regeneration with mesenchymal stem cellsMandibular fracturesApplication of autologous mesenchymal stem cells320Completed
Stem cells and tibial fracturesTibial fracturesCD34+ hematopoietic stem cells19Completed
Autologous implantation of mesenchymal stem cells for the treatment of distal tibial fracturesTibial fracturesAutologous mesenchymal stem cells implantation224Completed
Autologous stem cell therapy for fracture non-union healingNon-union of fracturesCarrier plus in vitro expanded autologous BMSCsNot applicable35Completed
Treatment of non-union of long bone fractures by autologous mesenchymal stem cellsNonunion fracturesCell injection16Completed
Percutaneous autologous bone-marrow grafting for open tibial shaft fractureTibial fractures; fractures, openOsteosynthesisNot applicable85Completed
Use of adult bone marrow mononuclear cells in patients with long bone nonunionLong bone nonunionOsteosynthesis27Completed
A comparative study of 2 doses of BM autologous H-MSC+ biomaterial vs iliac crest autograft for bone healing in non-unionNon-union fractureCultured mesenchymal stem cells; autologous iliac crest graft3108Recruiting
Clinical trial of intravenous infusion of fucosylated bone marrow mesenchymal cells in patients with osteoporosisOsteoporosis; spinal fracturesFucosylated MSCs for osteoporosis110Recruiting
Reconstruction of jaw bone using mesenchymal stem cellsBone atrophyBCP with autologous MSCs113Enrolling by invitation