Copyright ©The Author(s) 2020.
World J Stem Cells. Aug 26, 2020; 12(8): 761-775
Published online Aug 26, 2020. doi: 10.4252/wjsc.v12.i8.761
Figure 1
Figure 1 Stepwise in vitro differentiation of pancreatic cells from human embryonic stem cells. Stage-specific markers, regulating pathways, recombinant proteins, and small molecules added at different stages are listed. +: Positive regulation; -: Negative regulation; IDE: Induction of definitive endoderm; Shh: Sonic hedgehog; KGF: Keratinocyte growth factor; RA: Retinoic acid; PKC: Protein kinase C; ILV: Indolactum V; HGF: Hepatocyte growth factor; RSV: Resveratrol.