Published online Dec 26, 2016. doi: 10.4252/wjsc.v8.i12.399
Peer-review started: June 17, 2016
First decision: July 11, 2016
Revised: August 19, 2016
Accepted: September 21, 2016
Article in press: September 22, 2016
Published online: December 26, 2016
Core tip: Currently, there are little possibilities to treat age-associated disorders, since the morphostasis of normal tissues and its alteration with age advancement remain poorly understood. The components of the immune system, beside immunity, exhibit an important morphostatic function in the regulation of tissue physiology and regeneration as participants in the tissue morphostasis management. Age-induced immune system decline is accompanied by gonadal infertility and growing incidence of age-associated diseases and cancers. Utilization of young blood can alleviate aging, and a novel simple elaborated immunotherapy can cause regression of advanced cancers without a need of the debulking surgery and/or exhaustive chemotherapy.