Role of mesenchymal stem cells in cell life and their signaling

doi:10.4252/wjsc.v6.i1.24

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Jan 26, 2014 (publication date) through Apr 19, 2024

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World Journal of Stem Cells

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1948-0210

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Topic Highlight

World J Stem Cells. Jan 26, 2014; 6(1): 24-32
Published online Jan 26, 2014. doi: 10.4252/wjsc.v6.i1.24

Role of mesenchymal stem cells in cell life and their signaling

Shihori Tanabe

Shihori Tanabe, National Institute of Health Sciences, Tokyo 158-8501, Japan

Author contributions: Tanabe S solely contributed to this paper.

Correspondence to: Shihori Tanabe, PhD, National Institute of Health Sciences, 1-18-1, Kami-yoga, Setagaya-ku, Tokyo 158-8501, Japan. stanabe@nihs.go.jp

Telephone: +81-3-37001141 Fax: +81-3-37076950

Received: October 10, 2013
Revised: November 18, 2013
Accepted: December 12, 2013
Published online: January 26, 2014

Core Tip

Core tip: Mesenchymal stem cells (MSCs) are important cells that have a differentiation and self-renewal capacity and an immune-modulation function. MSCs differentiate into osteogenic-, adipogenic-, chondrogenic- and other cells. The application of MSCs in many situations, such as disease treatment, is full of possibilities for future development. The gene and protein expression and cellular phenotypes of MSCs are described.