Multidifferentiation potential of dental-derived stem cells

doi:10.4252/wjsc.v13.i5.342

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May 26, 2021 (publication date) through Apr 25, 2024

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World Journal of Stem Cells

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1948-0210

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Stem Cells. May 26, 2021; 13(5): 342-365
Published online May 26, 2021. doi: 10.4252/wjsc.v13.i5.342

Multidifferentiation potential of dental-derived stem cells

Jing-Yao Yin, Xing-Hong Luo, Wei-Qing Feng, Sheng-Hong Miao, Ting-Ting Ning, Qian Lei, Tao Jiang, Dan-Dan Ma

Jing-Yao Yin, Xing-Hong Luo, Wei-Qing Feng, Sheng-Hong Miao, Qian Lei, Tao Jiang, Department of Stomatology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, Guangdong Province, China

Ting-Ting Ning, Dan-Dan Ma, Department of Endodontics, Stomatological Hospital, Southern Medical University, Guangzhou 510280, Guangdong Province, China

Author contributions: Yin JY prepared the initial draft, tables and figures; All authors wrote parts of the manuscript, read and approved the final version of the manuscript.

Supported by National Natural Science Foundation of China, No. 81970930.

Conflict-of-interest statement: Authors declare that they have no conflicts of interest for this article.

Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/

Corresponding author: Dan-Dan Ma, PhD, Professor, Department of Endodontics, Stomatological Hospital, Southern Medical University, No. 366 Jiangnan Avenue South, Guangzhou 510280, Guangdong Province, China. mdd@smu.edu.cn

Received: December 21, 2020
Peer-review started: December 21, 2020
First decision: February 14, 2021
Revised: March 10, 2021
Accepted: April 4, 2021
Article in press: April 4, 2021
Published online: May 26, 2021

Core Tip

Core Tip: Dental mesenchymal stem cells have been widely used in tissue engineering and regenerative medicine due to their multipotential differentiation ability. We herein discuss the multipotency of dental mesenchymal stem cells and some related factors influencing the odontogenic/osteogenic differentiation, which provide guidance for fully utilizing the multipotency of dental mesenchymal stem cells.